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1.Substituted hexahydro-arylquinolizine derivatives, processes for their preparation and pharmaceutical composition containing them 失效
标题翻译: 取代Hexahydroarylchinolizinderivate,涉及它们的制备方法和含有它们的药物组合物。公开(公告)号:EP0214556A1
公开(公告)日:1987-03-18
申请号:EP86111890.9
申请日:1986-08-28
申请人: Merck & Co., Inc.
发明人: Huff, Joel R. , Baldwin, John J. , Vacca, Joseph P. , Guare, James P., Jr. , Sakurai, Yojiro MSD(Japan)Co.Ltd.
IPC分类号: C07D491/147 , C07D495/14 , C07D471/14 , C07D455/06 , C07D513/14 , A61K31/435
CPC分类号: C07D471/14 , C07D455/06 , C07D491/14 , C07D495/14
摘要: Substituted hexahydro arylquinolizines and pharmaceutically acceptable salts thereof are selective α 2 -adranergic receptor antagonists and thereby useful as antidepressants, antihypertensives, ocular antihypertensives, antidiabetics, antiobesity and platelet aggregation inhibitors and modifiers of gastrointestinal motility.
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2.Substituted hexahydro-arylquinolizine derivatives, processes for their preparation and pharmaceutical composition containing them 失效
标题翻译: 取代的四氢呋喃衍生物衍生物,其制备方法和含有它们的药物组合物公开(公告)号:EP0214556B1
公开(公告)日:1990-11-22
申请号:EP86111890.9
申请日:1986-08-28
申请人: Merck & Co., Inc.
发明人: Huff, Joel R. , Baldwin, John J. , Vacca, Joseph P. , Guare, James P., Jr. , Sakurai, Yojiro MSD(Japan)Co.Ltd.
IPC分类号: C07D491/147 , C07D495/14 , C07D471/14 , C07D455/06 , C07D513/14 , A61K31/435
CPC分类号: C07D471/14 , C07D455/06 , C07D491/14 , C07D495/14
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