专利检索 ap:("Merck & Co., Inc. (a New Jersey corp.)") AND inv:"NELSON, Todd, D." 第 1 页

1.

发明公开
PROCESS FOR THE SYNTHESIS OF N-BENZYL-3-(4-FLUOROPHENYL)-1,4-OXAZIN-2-ONE 审中-公开
标题翻译： METHOD FOR N-苄基-3-（4-氟苯基）-1,4-恶嗪-2-酮的合成

公开(公告)号：EP1112259A1

公开(公告)日：2001-07-04

申请号：EP99948170.8

申请日：1999-09-09

申请人： Merck & Co., Inc. (a New Jersey corp.)

发明人： NELSON, Todd, D. , BHUPATHY, Mahadevan

IPC分类号： C07D265/32

CPC分类号： C07D265/32

摘要： The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of formula (5). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.