专利检索 ap:("Merck & Co., Inc. (a New Jersey corp.)") AND inv:"VAN DER PLOEG, Leonardus, H., T." 第 1 页

1.

发明公开
TRANSGENIC ANIMAL EXPRESSING A FAMILIAL FORM OF HUMAN AMYLOID PRECURSOR PROTEIN 失效
标题翻译：转基因动物能表达人淀粉样前体蛋白的一种家庭形态

公开(公告)号：EP0778886A1

公开(公告)日：1997-06-18

申请号：EP95932340.0

申请日：1995-08-28

申请人： Merck & Co., Inc. (a New Jersey corp.)

发明人： SINGH, Gurparkash , CHEN, Howard, Y. , HEAVENS, Robert P., Terlings Park , SIRINATHSINGHJI, Dalip J., S., Terlings Park , SMITH, David W., Terlings Park Eastwick Road , TRUMBAUER, Myrna, E. , VAN DER PLOEG, Leonardus, H., T. , VONGS, Aurawan , ZHENG, Hui

IPC分类号： A01K67 , C07K14 , C12N5 , C12N15

CPC分类号： C12N15/8509 , A01K67/0275 , A01K67/0278 , A01K2207/15 , A01K2217/00 , A01K2217/05 , A01K2227/105 , A01K2267/0312 , C12N2830/008

摘要： Transgenic mice with a gene encoding human amyloid precursor protein gene are provided. The transgenic mice may be used to evaluate compounds affecting Alzheimer's Disease and other cognitive disorders.