专利检索 ap:("Merck Frosst Canada Ltd.") AND inv:"CHEN, Austin Chih-Yu" 第 1 页

1.

发明公开
3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS 审中-公开
标题翻译： 3.4 SUBSTITUIERTE PIPERIDINDERIVATE ALS RENININHIBITOREN

公开(公告)号：EP2300453A1

公开(公告)日：2011-03-30

申请号：EP09749373.8

申请日：2009-05-21

申请人： Merck Frosst Canada Ltd.

发明人： CHEN, Austin Chih-Yu , DUBÉ, Daniel , FOURNIER, Pierre-André , GRIMM, Erich L. , LACOMBE, Patrick , LALIBERTÉ, Sébastien , MACDONALD, Dwight , MACKAY, D. Bruce , MCKAY, Daniel James , WU, Tom Yao-Hsiang

IPC分类号： C07D401/04 , A61K31/4709

CPC分类号： C07D401/04 , C07D401/14

摘要： The present invention relates to 3,4-substituted piperidinyl - based renin inhibitor compounds bearing at 4-position lsoqumolone and having the Formula (I) : The invention further relates to pharmaceutical compositions containing said compounds, as well as their use in treating cardiovascular events and renal insufficiency.