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15 条记录 (耗时 0.021 秒)

    2,2'-FUROIN-DERIVATE UND DEREN VERWENDUNG ZUR HAUTAUFHELLUNG
    5.
    发明公开
    2,2'-FUROIN-DERIVATE UND DEREN VERWENDUNG ZUR HAUTAUFHELLUNG 有权
    2,2'-联糠醛衍生物及其使用的用于皮肤美白

    公开(公告)号：EP2616040A1

    公开(公告)日：2013-07-24

    申请号：EP11752111.2

    申请日：2011-08-18

    申请人： Merck Patent GmbH

    发明人： SCHEURICH, René, Peter

    IPC分类号： A61K8/49

    CPC分类号： A61Q19/02 ,  A61K8/4973 ,  A61Q17/04 ,  C07D407/06

    摘要： The invention relates to the use of compounds of the formula (I), wherein R1, R2, m, and n have the meanings specified in the claims, and/or physiologically harmless salts, tautomers, stereoisomers, and/or solvates thereof, including mixtures thereof in all ratios, to inhibit tyrosinase and to lighten skin. The invention further relates to the use of the compounds of formula (I) in the prophylaxis, therapy, or progress monitoring of pigment disorders of the skin. The invention further relates to preparations having the compounds of formula (I) in combination with at least one further active ingredient and to a method for producing the preparations by mixing the compounds of formula (I) with a carrier that is physiologically harmless for topical applications.

    TRIAZINE ALS REAKTIONSBESCHLEUNIGER
    6.
    发明公开
    TRIAZINE ALS REAKTIONSBESCHLEUNIGER 有权
    三嗪响应加速器

    公开(公告)号：EP2568953A2

    公开(公告)日：2013-03-20

    申请号：EP11714703.3

    申请日：2011-04-13

    申请人： Merck Patent GmbH

    发明人： SCHEURICH, René, Peter ,  RUDOLPH, Thomas

    IPC分类号： A61K8/35 ,  A61K8/49 ,  A61Q17/04 ,  C11B5/00

    CPC分类号： A61K8/4966 ,  A23L33/10 ,  A61K8/35 ,  A61K2800/522 ,  A61Q5/00 ,  A61Q5/06 ,  A61Q17/04

    摘要： The invention relates to the use of at least one specific triazine or melamine and/or the salt thereof as an accelerator for a photo-induced reaction of 3-(4-tert-butyphenyl)-3-hydroxy-1-(4-methoxyphenyl)-propan-1-one, 1-(4-tert-butylphenyl)-3-hydroxy-3-(4-methoxyphenyl)-propan-1-one or a mixture of these compounds to form avobenzone. The invention also relates to a preparation containing at least one specific triazine or melamine and a method for stabilising the UV absorption capability of a preparation using a mixture of at least one specific triazine or melamine with 3-(4-tert-butylphenyl)-3-hydroxy-1-(4-methoxyphenyl)-propan-1-one, 1-(4- tert-butylphenyl)-3-hydroxy-3-(4-methoxyphenyl)-propan-1-one or a mixture of these compounds, especially preferably with 3-(4-tert-butylphenyl)-3-hydroxy-1-(4-methoxyphenyl)-propan-1-one.