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公开(公告)号：EP2435018A2
公开(公告)日：2012-04-04
申请号：EP10721307.6
申请日：2010-04-29
申请人： Merck Patent GmbH
摘要： The present invention relates to special ammonium carboxylates, their synthesis and application, particularly as anti-dandruff agents.
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2.发明公开USE OF SUBSTITUTED AMINOMETHYL CHROMANS IN THE TREATMENT OF MOVEMENT DISORDERS 有权氨甲基二氢吡喃可用于治疗抗精神病药的副作用USE
公开(公告)号：EP1425008A1
公开(公告)日：2004-06-09
申请号：EP02767352.4
申请日：2002-08-09
申请人： MERCK PATENT GmbH
发明人： BARTOSZYK, Gerd , RUSS, Hermann , SEYFRIED, Christoph , BÖTTCHER, Henning , BOKEL, Heinz-Hermann , SCHMID-GROSSMANN, Uschi
IPC分类号： A61K31/353 , A61P25/14 , A61P25/16
CPC分类号： A61K31/353
摘要： Substituted aminomethyl chromans, one of their optical isomers or pharmaceutically acceptable salts, used for the manufacture of a medicament for the treatment of adverse effects of anti-Parkinsonian drugs in extrapyramidal movement disorders and/or for the manufacture of a medicament for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics. A preferred compound is (-)-(R)-2-{4-[[3,4-dihydro-2H-benzopyran-2-yl)-methyl!amino!butyl}-1,2-benzoisothiazol-3-(2H)-on-1,1-dioxide or a physiologically acceptable salt thereof.
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公开(公告)号：EP2435036A2
公开(公告)日：2012-04-04
申请号：EP10721308.4
申请日：2010-04-29
申请人： Merck Patent GmbH
IPC分类号： A61K31/14 , C07C211/63
CPC分类号： A61K31/14 , A01N33/12 , A01N33/20 , A61K8/416 , A61Q5/004 , A61Q5/006 , A61Q11/00 , A61Q15/00 , A61Q17/005 , C07C69/12 , C07C69/24 , C07C215/40 , C07C217/08
摘要： The present invention relates to special ammonium carboxylates, their synthesis and application, particularly as biocides.
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4.发明授权VERWENDUNG VON IONISCHEN FLÜSSIGKEITEN MIT TRICYANOMETHIDANIONEN ALS LÖSUNGSMITTEL ZUR EXTRAKTION VON ALKOHOLEN AUS WÄSSRIGEN LÖSUNGEN 有权离子液体TRICYANOMETHIDANIONEN作为从水溶液中的低碳醇提取SOLVENTS使用
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5.发明公开VERWENDUNG VON IONISCHEN FLÜSSIGKEITEN MIT TRICYANOMETHIDANIONEN ALS LÖSUNGSMITTEL ZUR EXTRAKTION VON ALKOHOLEN AUS WÄSSRIGEN LÖSUNGEN 有权离子液体TRICYANOMETHIDANIONEN作为从水溶液中的低碳醇提取SOLVENTS使用
公开(公告)号：EP2300117A2
公开(公告)日：2011-03-30
申请号：EP09772057.7
申请日：2009-05-28
申请人： Merck Patent GmbH
CPC分类号： C07C29/86 , C12P7/06 , C12P7/16 , C12P7/28 , Y02E50/10 , Y02E50/17 , Y02P20/542 , C07C31/12 , C07C31/10 , C07C31/08
摘要： The invention relates to a method for liquid-liquid extraction of alcohols from aqueous solutions using at least one ionic liquid containing a tricyanomethide anion as solvent.
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6.发明授权USE OF SUBSTITUTED AMINOMETHYL CHROMANS IN THE TREATMENT OF SIDE EFFECTS OF NEUROLEPTICS 有权氨甲基二氢吡喃可用于治疗抗精神病药的副作用USE
公开(公告)号：EP1425008B1
公开(公告)日：2006-10-04
申请号：EP02767352.4
申请日：2002-08-09
申请人： Merck Patent GmbH
发明人： BARTOSZYK, Gerd , RUSS, Hermann , SEYFRIED, Christoph , BÖTTCHER, Henning , BOKEL, Heinz-Hermann , SCHMID-GROSSMANN, Uschi
IPC分类号： A61K31/353 , A61K31/195 , A61P25/14 , A61P25/16
CPC分类号： A61K31/353
摘要： Substituted aminomethyl chromans, one of their optical isomers or pharmaceutically acceptable salts, used for the manufacture of a medicament for the treatment of adverse effects of anti-Parkinsonian drugs in extrapyramidal movement disorders and/or for the manufacture of a medicament for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics. A preferred compound is (-)-(R)-2-{4-[[3,4-dihydro-2H-benzopyran-2-yl)-methyl!amino!butyl}-1,2-benzoisothiazol-3-(2H)-on-1,1-dioxide or a physiologically acceptable salt thereof.
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