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1.MAMMALIAN INTERLEUKIN-12 P40 AND INTERLEUKIN B30 COMPLEXES, ANTIBODIES, USES IN PHARMACEUTICAL COMPOSITIONS 审中-公开
标题翻译: 哺乳动物白细胞介素-12 P40和白细胞介素B30复合物,抗体,用于药物组合物公开(公告)号:EP3184637A1
公开(公告)日:2017-06-28
申请号:EP17156073.3
申请日:2000-09-08
发明人: OPPMANN, Birgit , DE WAAL MALEFYT, Rene , RENNICK, Donna M. , KASTELEIN, Robert A. , WIEKOWSKI, Maria T. , LIRA, Sergio A. , NARULA, Satwant K.
IPC分类号: C12N15/62 , A61K38/20 , C07K16/24 , A01K67/027 , C12Q1/68 , G01N33/68 , A61K39/395 , A61P29/00 , C07K14/54 , A61P37/06
CPC分类号: C07K14/54 , A01K2217/05 , A61K38/00 , C07K14/5434 , C07K2319/00 , C07K2319/02
摘要: Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
摘要翻译: 提供了编码来自哺乳动物的细胞因子的纯化基因,与其相关的试剂,包括纯化的蛋白质,特异性抗体和编码该分子的核酸。 还提供了使用所述试剂和诊断试剂盒的方法。
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公开(公告)号:EP2250199B1
公开(公告)日:2015-09-02
申请号:EP09709406.4
申请日:2009-02-06
IPC分类号: A61K39/395 , C07K16/28 , A61P37/06
CPC分类号: C07K16/2866 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/92
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公开(公告)号:EP2773774A1
公开(公告)日:2014-09-10
申请号:EP12844827.1
申请日:2012-10-31
申请人: Merck Sharp & Dohme Corp. , Beaumont, Maribel , Mattson, Jeanine, D. , Louten, Jennifer, R. , McClannahan, Terrill, K. , De Waal Malefyt, Rene
发明人: BEAUMONT, Maribel , MATTSON, Jeanine, D. , LOUTEN, Jennifer, R. , MCCLANNAHAN, Terrill, K. , DE WAAL MALEFYT, Rene
CPC分类号: C07K16/24 , C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , G01N33/54306 , G01N33/6863 , G01N2800/24 , G01N2800/52
摘要: The present invention relates to biomarker responsive to treatment with an anti-Thymic Stromal Lymphopoietin (TSLP) antibody.
摘要翻译: 本发明涉及响应于用TSLP拮抗剂治疗的生物标志物。
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4.Antagonist antibodies of a mammalian cytokine or its receptor for the treatment of allergy 有权
标题翻译: 对过敏治疗Säugerzytokine或其受体的拮抗剂抗体公开(公告)号:EP1379647B1
公开(公告)日:2013-06-05
申请号:EP01273862.1
申请日:2001-11-09
发明人: RECHE-GALLARDO, Pedro, A. , DE WAAL MALEFYT, Rene , BAZAN, J., Fernando , KASTELEIN, Robert, A. , LIU, Yong-Jun
IPC分类号: A61K38/17
CPC分类号: C07K16/244 , C07K14/54 , C07K14/7155 , G01N33/6863 , G01N33/6869 , G01N2333/54 , G01N2500/02
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5.MAMMALIAN INTERLEUKIN-12 P40 AND INTERLEUKIN B30. COMBINATIONS THEREOF. ANTIBODIES. USES IN PHARMACEUTICAL COMPOSITIONS 有权
标题翻译: 白细胞介素-12和IL P40-B30。 它们的组合。 抗体。 用途药物组合物公开(公告)号:EP1210434B2
公开(公告)日:2016-12-14
申请号:EP00961688.9
申请日:2000-09-08
发明人: OPPMANN, Birgit , DE WAAL MALEFYT, Rene , RENNICK, Donna, M. , KASTELEIN, Robert, A. , WIEKOWSKI, Maria, T. , LIRA, Sergio, A. , NARULA, Satwant, K.
CPC分类号: C07K14/54 , A01K2217/05 , A61K38/00 , C07K14/5434 , C07K2319/00 , C07K2319/02
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公开(公告)号:EP2056838B1
公开(公告)日:2013-09-25
申请号:EP08714219.6
申请日:2008-02-26
发明人: BOWMAN, Edward, Paul , CUA, Daniel, J. , KASTELEIN, Robert, A. , MILLER, Kathy, Lynn , KLEINSCHEK, Melanie, A. , BAK-JENSEN, Kristian, Sass , BONIFACE, Katia , MCKENZIE, Brent, S. , DE WAAL MALEFYT, Rene
IPC分类号: A61K31/55 , A61K38/17 , A61K39/395 , A61K45/06 , A61P35/00 , A61P37/00 , C07K14/705 , C07K14/715 , C07K16/24
CPC分类号: A61K39/3955 , A61K31/55 , A61K31/5575 , A61K38/1793 , A61K39/395 , A61K45/06 , C07K16/244 , C07K2317/76 , A61K2300/00
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