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公开(公告)号:EP2326331A1
公开(公告)日:2011-06-01
申请号:EP09808606.9
申请日:2009-08-11
申请人: Merck Sharp & Dohme Corp.
发明人: BOWMAN, Keith, A. , GUARE, James, P. , HARTMAN, George, D. , PARMAR, Rubina, G. , VARGEESE, Chandra , WANG, Weimin , ZHANG, Ye
IPC分类号: A61K31/56
CPC分类号: A61K9/5123 , A61K9/1272 , A61K9/1277 , A61K9/5192 , A61K47/28 , C07C217/42
摘要: The instant invention provides for novel lipid nanoparticles and novel lipid nanoparticle components (specifically cationic lipids) that are useful for the delivery of nucleic acids, specifically siRNA, for therapeutic purposes.