专利检索 ap:("Merck Sharp & Dohme Corp." OR "MSD K.K.") AND inv:"KATO, Tetsuya" 第 1 页

1.

发明公开
INHIBITORS OF AKT ACTIVITY 审中-公开

公开(公告)号：EP2391623A1

公开(公告)日：2011-12-07

申请号：EP10736277.4

申请日：2010-01-25

申请人： Merck Sharp & Dohme Corp. , MSD K.K.

发明人： ARMSTRONG, Donna, J. , GOTO, Yasuhiro , HASHIHAYATA, Takashi , KATO, Tetsuya , KELLY, Michael, J., III , LAYTON, Mark, E. , LINDSLEY, Craig, W. , OGINO, Yoshio , ONOZAKI, Yu , RODZINAK, Kevin, J. , ROSSI, Michael, A. , SANDERSON, Philip, E. , WANG, Jiabing , YAROSCHAK, Melissa, M.

IPC分类号： C07D471/02

CPC分类号： C07D471/04 , C07D217/24 , C07D241/42 , C07D401/04 , C07D401/12 , C07D403/04 , C07D475/02 , C07D475/04 , C07D487/04 , C07D519/00

摘要： The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.

2.

发明授权
NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION 有权
标题翻译：与选择性AURORA-A-抗炎作用NEW氨基吡啶衍生物

公开(公告)号：EP2254888B1

公开(公告)日：2014-12-24

申请号：EP09711943.2

申请日：2009-02-18

申请人： MSD K.K.

发明人： KATO, Tetsuya , KAWANISHI, Nobuhiko , MITA, Takashi , NONOSHITA, Katsumasa , OHKUBO, Mitsuru

IPC分类号： C07D401/14 , C07D413/14 , C07D417/14 , A61K31/4545 , A61K31/506 , A61P35/00 , A61P41/00

CPC分类号： C07D417/14 , C07D401/14 , C07D413/14

3.

发明授权
AMINOPYRIDINE DERIVATIVE HAVING AURORA A-SELECTIVE INHIBITORY ACTIVITY 有权
标题翻译： WITH AURORA选择性抑制效果氨基吡啶衍生物

公开(公告)号：EP2062887B1

公开(公告)日：2012-07-04

申请号：EP07806706.3

申请日：2007-08-29

申请人： MSD K.K.

发明人： IWASAWA, Yoshikazu , KATO, Tetsuya , KAWANISHI, Nobuhiko , MASUTANI, Kouta , MITA, Takashi , NONOSHITA, Katsumasa , OHKUBO, Mitsuru

IPC分类号： C07D401/12 , C07D403/12 , C07D417/12 , A61K31/4439 , A61K31/497 , A61K45/00 , A61P35/00 , A61P35/02 , A61P43/00

CPC分类号： C07D413/14 , A61K45/06 , C07D401/12 , C07D403/12 , C07D417/12

摘要： Disclosed is a compound represented by the general formula [I] below or a pharmaceutically acceptable salt or ester thereof. (I) (In the formula, R1 represents a hydrogen atom, F, CN or the like; R1' represents a hydrogen atom or an optionally substituted lower alkyl group; R2 represents O, S, SO, SO2 or the like;R3 represents an optionally substituted phenyl group; X1, X2 and X3 independently represent CH, N or the like, provided that none or one of X1, X2 and X3 is N; and W represents a group represented by the following formula: , wherein W1, W2 and W3 independently represent CH, N or the like.)

4.

发明授权
AMINOPYRIMIDINE DERIVATIVES HAVING AURORA-A-SELECTIVE INHIBITORY ACTIVITY 有权
标题翻译： WITH AURORA选择性抑制效果氨基嘧啶衍生物

公开(公告)号：EP2017279B1

公开(公告)日：2013-09-04

申请号：EP07742848.0

申请日：2007-04-25

申请人： MSD K.K.

发明人： KATO, Tetsuya , KAWANISHI, Nobuhiko , MITA, Takashi , NAGAI, Keita , NONOSHITA, Katsumasa , OHKUBO, Mitsuru

IPC分类号： C07D487/08 , A61K31/497 , A61K31/4995 , A61K31/506 , A61K45/08 , A61P35/00 , A61P43/00

CPC分类号： C07D487/08