专利检索 ap:("Merck AND Co., Inc.") AND inv:"MONTGOMERY, Donna, L." 第 1 页

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发明公开
POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS 有权
标题翻译：多肽诱导抗金黄色葡萄球菌的保护性免疫反应

公开(公告)号：EP1725575A2

公开(公告)日：2006-11-29

申请号：EP05713397.7

申请日：2005-02-14

申请人： Merck and Co., Inc.

发明人： ANDERSON, Annaliesa, S. , MONTGOMERY, Donna, L.

IPC分类号： C07K1/00 , C07K2/00 , A61K39/02 , A61K39/00 , A61K39/085 , A61K39/09

CPC分类号： A61K39/085 , A61K39/00 , C07K14/31

摘要： The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full length S. aureus polypeptide. The full-length polypeptide is referred to herein as full-length “sai-1”. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. aureus.