公开(公告)号：EP2459116A1

公开(公告)日：2012-06-06

申请号：EP10804771.3

申请日：2010-07-16

申请人： Merial Limited

发明人： HOLMES, Robert, William, Lachlan

IPC分类号： A61D7/00 ,  A61K9/00 ,  A61J3/00 ,  A61M31/00

CPC分类号： A61M31/002 ,  A61D7/00 ,  A61J3/07 ,  A61K9/0068 ,  A61K9/4808 ,  A61K9/4816

摘要： The invention relates to an intraruminal sustained release capsule which is capable of delivering a sustained release dose of a first medicament to an animal, as well as either or both of a dump dose of a second medicament or mineral, and an exit dose of a third medicament or mineral. The capsule can have a dissolvable overcap molded from plasticized starch enabling a dump dose of medicament to be held between the overcap and one end of the capsule. A piston within the body of the capsule can be modified to enable it to accommodate an exit dose of medicament within its hollow interior which is aligned with an aperture at the end of the capsule which enables release of the medicaments to the rumen. After insertion of the capsule in the animal the overcap (if present) dissolves and separates from the capsule to release the dump dose of medicament. The sustained release medicament is then dispensed via the apertured end, followed by the release of the exit dose of medicament (if present).