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    Needle Assemblies for Wet/Dry Automatic Injectors
    1.
    发明公开
    Needle Assemblies for Wet/Dry Automatic Injectors 有权
    用于湿式/干式自动注射器的针头组件

    公开(公告)号：EP2308530A2

    公开(公告)日：2011-04-13

    申请号：EP11153053.1

    申请日：2004-10-21

    申请人： Meridian Medical Technologies, Inc.

    发明人： Griffiths, Steven M. ,  Hill, Robert L. ,  Wilmont, John G.

    IPC分类号： A61M5/28 ,  A61M5/20 ,  A61M5/32 ,  A61M5/315

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： One aspect relates to an automatic injection device containing a pre-loaded charge of medicament for automatically administering the medicament upon actuation thereof. A further aspect relates to a method of providing a medicament containing chamber of an automatic injection device. The automatic injection device comprises a housing; a medicament chamber having a first compartment and a second compartment, the first compartment containing a first medicament portion and the second compartment containing a second medicament portion to be mixed with the first medicament portion; a seal structure between the first compartment and the second compartment, the seal structure initially in a sealing condition that maintains the first compartment separate from the second compartment; a needle assembly that dispenses the medicament charge from the medicament chamber, the needle assembly comprising a needle and a needle support, the needle support for mounting the needle to the medicament chamber, the needle support defining a needle assembly chamber having an inner surface that tapers radially inward as it extends axially forward toward a rearward end of the needle, the needle support forming a channel from the medicament chamber to the needle; and an activation assembly. Activation of the activation assembly causes (a) the seal structure to be converted from the sealing condition to a mixing condition, (b) the first and second medicament portions to be mixed, and (c) the mixed first and second medicament portions to be forced through the needle assembly.

    摘要翻译： 一个方面涉及一种自动注射装置，其包含用于在致动药物时自动给药的药物的预加载药物。 另一方面涉及提供自动注射装置的药物容纳室的方法。 自动注射装置包括壳体; 具有第一隔室和第二隔室的药物腔室，所述第一隔室包含第一药物部分，并且所述第二隔室包含待与所述第一药物部分混合的第二药物部分; 所述第一隔室和所述第二隔室之间的密封结构，所述密封结构最初处于保持所述第一隔室与所述第二隔室分离的密封状态; 从所述药物室分配药物填充物的针组件，所述针组件包括针和针支撑件，所述针支撑件用于将所述针安装到所述药物腔室，所述针支撑件限定具有内表面的针组件腔室， 径向向内朝向所述针的后端轴向向前延伸，所述针支撑件形成从所述药剂室到所述针的通道; 和一个激活组件。 激活组件的激活导致（a）密封结构从密封状态转变为混合状态，（b）要混合的第一和第二药物部分，以及（c）混合的第一和第二药物部分为 被迫穿过针组件。

    Auto-injector apparatus with a flexible container
    3.
    发明公开
    Auto-injector apparatus with a flexible container 审中-公开
    Autoinjektorvorrichtung mit flexiblemBehälter

    公开(公告)号：EP2803374A1

    公开(公告)日：2014-11-19

    申请号：EP14174993.7

    申请日：2009-11-24

    申请人： Meridian Medical Technologies, Inc.

    发明人： Mathews, Colin J. ,  Hurlstone, Chris J. ,  Turner, Ben G. ,  Harvey, Oliver T. ,  Reber, Dominic C. ,  Wilmot, John G. ,  Mesa, Clarence M. ,  Hill, Robert L. ,  Stewart, James R. Jr.

    IPC分类号： A61M5/00 ,  A61M5/145 ,  A61M5/148 ,  A61M5/152 ,  A61M5/20 ,  A61M5/32 ,  A61M5/34 ,  A61M5/142 ,  A61M5/24 ,  A61M5/31

    摘要： The invention relates to an auto-injector apparatus (10), comprising:
    a flexible container (108) containing a liquid medicant;
    a needle (144)communicated with the container;
    a housing (102), the container being received in the housing;
    a pump (210) disposed in the housing and positioned to engage the flexible container and expel the medicant from the container through the needle upon relative movement between the pump and the container; and
    a main drive spring (226) operably associated with the needle to extend the needle from a first needle position wherein the needle is completely received in the housing to a second needle position wherein the needle protrudes from the housing.
    The pump comprises a roller.

    摘要翻译： 本发明涉及一种自动注射器装置（10），包括：容纳液体药剂的柔性容器（108）; 与所述容器连通的针（144）; 壳体（102），容器被容纳在壳体中; 泵（210），设置在所述壳体中并且定位成接合所述柔性容器并且在所述泵和所述容器之间相对运动时将所述药物从所述容器通过所述针排出; 以及与所述针可操作地相关联的主驱动弹簧（226），以从所述第一针位置延伸所述针，其中所述针完全容纳在所述壳体中到所述针从所述壳体突出的第二针位置。 泵包括辊子。

    Needle Assemblies for Wet/Dry Automatic Injectors
    5.
    发明公开
    Needle Assemblies for Wet/Dry Automatic Injectors 有权
    用于湿式/干式自动注射器的针头组件

    公开(公告)号：EP2308530A3

    公开(公告)日：2011-09-07

    申请号：EP11153053.1

    申请日：2004-10-21

    申请人： Meridian Medical Technologies, Inc.

    发明人： Griffiths, Steven M. ,  Hill, Robert L. ,  Wilmont, John G.

    IPC分类号： A61M5/34 ,  A61M5/32 ,  A61M5/28 ,  A61M5/20 ,  A61M5/315

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： One aspect relates to an automatic injection device containing a pre-loaded charge of medicament for automatically administering the medicament upon actuation thereof. A further aspect relates to a method of providing a medicament containing chamber (350) of an automatic injection device. The automatic injection device comprises a housing (110); a medicament chamber (350) having a first compartment and a second compartment, the first compartment containing a first medicament portion (151) and the second compartment containing a second medicament portion (152) to be mixed with the first medicament portion (151); a seal structure (380) between the first compartment and the second compartment, the seal structure (380) initially in a sealing condition that maintains the first compartment separate from the second compartment; a needle assembly (340) that dispenses the medicament charge from the medicament chamber, the needle assembly (340) comprising a needle (141) and a needle support (343), the needle support (343) for mounting the needle (141) to the medicament chamber (350), the needle support (343) defining a needle assembly chamber (394) having an inner surface that tapers radially inward as it extends axially forward toward a rearward end of the needle, the needle support (343) forming a channel from the medicament chamber (350) to the needle; and an activation assembly (120). Activation of the activation assembly causes (a) the seal structure to be converted from the sealing condition to a mixing condition, (b) the first and second medicament portions (151,152) to be mixed, and (c) the mixed first and second medicament portions to be forced through the needle assembly (340).

    摘要翻译： 一个方面涉及一种自动注射装置，其包含用于在致动药物时自动给药的药物的预加载药物。 另一方面涉及提供自动注射装置的药物容纳室（350）的方法。 自动注射装置包括壳体（110）; 具有第一隔室和第二隔室的药物腔室，所述第一隔室包含第一药物部分并且所述第二隔室包含与所述第一药物部分混合的第二药物部分; 在所述第一隔室和所述第二隔室之间的密封结构（380），所述密封结构（380）最初处于保持所述第一隔室与所述第二隔室分离的密封状态; （340），所述针组件（340）包括针（141）和针支撑件（343），针支撑件（343）用于将针（141）安装到药剂室 所述药物腔室（350），所述针支撑件（343）限定具有内表面的针组件腔室（394），所述内表面随着其朝所述针的后端轴向地向前延伸而径向向内渐缩，所述针支撑件（343）形成 从药物腔室（350）到针头的通道; 和启动组件（120）。 激活组件的激活导致（a）密封结构从密封状态转变为混合状态，（b）待混合的第一和第二药剂部分（151,152），以及（c）混合的第一和第二药剂 迫使部分通过针组件（340）。

    Flow-Path Inserts for Wet/Dry Automatic Injectors
    9.
    发明公开
    Flow-Path Inserts for Wet/Dry Automatic Injectors 有权
    用于湿式/干式自动注射器的流路插入件

    公开(公告)号：EP2308529A3

    公开(公告)日：2011-09-07

    申请号：EP11153043.2

    申请日：2004-10-21

    申请人： Meridian Medical Technologies, Inc.

    发明人： Griffiths, Steven M. ,  Hill, Robert L. ,  Wilmont, John G.

    IPC分类号： A61M5/28 ,  A61M5/20 ,  A61M5/315

    CPC分类号： A61M5/31596 ,  A61M5/19 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/284 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/31513 ,  A61M5/3202 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/343 ,  A61M5/348 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/287 ,  A61M2005/3106 ,  A61M2005/3131 ,  A61M2005/3132 ,  A61M2202/064 ,  A61M2205/7536 ,  A61M2205/7545

    摘要： One aspect relates to an automatic injection device containing a pre-loaded charge of medicament for automatically administering the medicament upon actuation thereof. A further aspect relates to a method of providing a medicament containing chamber (350) of an automatic injection device. The automatic injection device comprises a housing (110); a chamber (350) having a first compartment and a second compartment, the first compartment containing a first medicament portion (151) and the second compartment containing a second medicament portion (152) to be mixed with the first medicament portion (151); a seal structure (380) between the first compartment and the second compartment, the seal structure (380) initially in a sealing condition that maintains the first compartment separate from the second compartment, the seal structure converting to a mixing condition in response to activation of the device; a needle assembly (340) that dispenses the medicament charge from the chamber, the needle assembly (340) having a rearward opening with a diameter that is less than a diameter of the chamber; an insert (384) mounted in a forward end of the chamber (350) adjacent the needle assembly (340), the insert (384) tapering radially inward as it extends axially forward; and an activation assembly (120). The activation of the activation assembly (120) causes (a) the seal structure (380) to be converted from the sealing condition to the mixing condition, (b) the first and second medicament portions (151,152) to be mixed, and (c) the mixed first and second medicament portions (151,152) to be directed by the insert (384) radially inwardly toward the rearward opening of the needle assembly (340).

    摘要翻译： 一个方面涉及一种自动注射装置，其包含用于在致动药物时自动给药的药物的预加载药物。 另一方面涉及提供自动注射装置的药物容纳室（350）的方法。 自动注射装置包括壳体（110）; 具有第一隔室和第二隔室的腔室（350），所述第一隔室包含第一药物部分（151），并且所述第二隔室包含与所述第一药物部分（151）混合的第二药物部分（152）; 在第一隔室和第二隔室之间的密封结构（380），密封结构（380）最初处于保持第一隔室与第二隔室分离的密封状态，密封结构转换成混合状态以响应 装置; 针头组件（340），其从所述腔室分配药物填充物，所述针头组件（340）具有直径小于所述腔室的直径的后部开口; 插入件（384），所述插入件（384）安装在所述腔室（350）的邻近所述针组件（340）的前端中，所述插入件（384）随着其轴向向前延伸而径向向内逐渐变细; 和启动组件（120）。 激活组件（120）的激活导致（a）密封结构（380）从密封状态转变为混合状态，（b）待混合的第一和第二药物部分（151,152），以及（c） ）混合的第一药物部分和第二药物部分（151,152）被插入件（384）径向向内朝向针组件（340）的后部开口引导。

    Automatic injector
    10.
    发明公开
    Automatic injector 审中-公开
    自动吸烟者

    公开(公告)号：EP2204201A1

    公开(公告)日：2010-07-07

    申请号：EP10155967.2

    申请日：2005-08-04

    申请人： Meridian Medical Technologies, Inc.

    发明人： Young, Matthew E. ,  Raven, Sophie R. ,  Murphy, Martin J. ,  Hurlstone, Christopher J. ,  Daintrey, Joseph W. ,  Rochford, Craig M. ,  Kirkwood, Stephen P. ,  Mathews, Colin J. ,  Hill, Robert L. ,  Wilmot, John G.

    IPC分类号： A61M5/00 ,  A61M5/32

    摘要： An auto-injector is disclosed. The automatic injector comprises a housing having a retention step formed on an inner surface of the housing; a cartridge having an opening therein and containing a medicament, the medicament rearwardly confined by a plunger received through the opening, the cartridge including a needle assembly operative to dispense the medicament there through during a medicament dispensing operation, the needle assembly including a needle; a cartridge container disposed within the housing and operative to receive the cartridge therein, the cartridge container having a ledge that abuts the retention step of the housing to limit movement of the cartridge container within the housing during a medicament dispensing operation, the cartridge container having a closed front end except for an opening sized to receive the needle there through during a medicament dispensing operation, the closed front end operative to engage the cartridge and oppose continued movement of the cartridge after the needle passes through the front end opening; an actuation assembly providing a stored energy source capable of driving the plunger within the cartridge to dispense the medicament through the needle assembly, the actuation assembly secured to the housing; and a needle cover at least partially received within the housing and operative to receive therein at least the front end of the cartridge container, the needle cover extending beyond the housing and having an enclosed end surface operative to contact an injection site prior to a medicament dispensing operation, the end surface having an opening sized to receive the needle there through during a medicament dispensing operation; wherein residual force from the energy source after activation of the medicament dispensing operation is contained by the cartridge container, the cartridge, the housing, and the actuation assembly to prevent kickback of the automatic injector from the injection site during a medicament dispensing operation.

    摘要翻译： 公开了一种自动注射器。 自动注射器包括壳体，其具有形成在壳体的内表面上的保持步骤; 药筒在其中具有开口并且容纳药物，所述药物由通过所述开口容纳的柱塞向后限制，所述药筒包括针组合件，所述针组件在药物分配操作期间在其中分配药物，所述针组件包括针头; 盒式存储器容器，其设置在壳体内并且可操作以在其中容纳盒，所述盒容器具有与所述壳体的保持步骤相邻的凸缘，以在药剂分配操作期间限制所述盒容器在所述壳体内的运动，所述盒容器具有 封闭的前端除了在药物分配操作期间尺寸适于接收针头的开口，封闭的前端可操作以接合盒并且在针穿过前端开口之后反对盒的继续移动; 致动组件，其提供能够驱动筒内的柱塞的储存能量源，以通过针组件分配药物，该致动组件固定到壳体; 以及针罩，其至少部分地容纳在所述壳体内并且用于至少在其中容纳所述盒容器的前端，所述针盖延伸超过所述壳体并且具有封闭端面，所述封闭端面在药物分配之前可操作以接触注射部位 所述端面具有开口尺寸以便在药物分配操作期间将针头接纳在那里; 其中在药剂分配操作激活之后来自能量源的剩余力被药筒容器，药筒，外壳和致动组件容纳，以防止在药物分配操作期间自动注射器从注射部位的反冲。