公开(公告)号：EP3513797A1

公开(公告)日：2019-07-24

申请号：EP18213454.4

申请日：2012-06-04

申请人： Mesoblast, Inc. ,  Central Adelaide Local Health Network Inc

发明人： KOBLAR, Simon Andrea ,  GRONTHOS, Stan ,  ARTHUR, Agnieszka

IPC分类号： A61K35/28 ,  C12N5/077 ,  C12N5/0789 ,  A61P25/14 ,  A61K38/00 ,  C12N5/0775

摘要： The present disclosure provides methods of improving cerebral function or preventing loss of cerebral function and/or treating or preventing a movement disorder and/or regenerating cerebral neurons in a subject who has suffered a stroke, the method comprising administering to the subject a population of cells enriched for STRO-1 + cells and/or progeny thereof and/or soluble factors derived therefrom.

公开(公告)号：EP2714058A1

公开(公告)日：2014-04-09

申请号：EP12793424.8

申请日：2012-06-04

申请人： Mesoblast, Inc. ,  Central Adelaide Local Health Network Inc

发明人： KOBLAR, Simon Andrea ,  GRONTHOS, Stan ,  ARTHUR, Agnieszka

IPC分类号： A61K35/28 ,  C12N5/077 ,  C12N5/0789 ,  A61P25/14

CPC分类号： A61K35/28 ,  A61K9/0085 ,  A61K38/00 ,  A61K38/195 ,  A61K2035/124 ,  C12N5/0663 ,  C12N5/0664

摘要： The present disclosure provides methods of improving cerebral function or preventing loss of cerebral function and/or treating or preventing a movement disorder and/or regenerating cerebral neurons in a subject who has suffered a stroke, the method comprising administering to the subject a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom.