PRODUCTION METHODS FOR 3,4-DIHYDROISOQUINOLINE DERIVATIVES, AND PRODUCTION INTERMEDIATES FOR SAME
    1.
    发明公开
    PRODUCTION METHODS FOR 3,4-DIHYDROISOQUINOLINE DERIVATIVES, AND PRODUCTION INTERMEDIATES FOR SAME 有权
    HERSTELLUNGSVERFAHRENFÜR3,4-DIHYDRO-ISOCHINOLINDERIVATE UND ZWISCHENPRODUKTEDAFÜR

    公开(公告)号:EP2762474A1

    公开(公告)日:2014-08-06

    申请号:EP12835210.1

    申请日:2012-09-28

    摘要: Provided are an efficient method for producing 3,4-dihydroisoquinoline derivatives and useful production intermediates thereof. Provided is a method for producing 3,4-dihydroisoquinoline derivatives represented by general formula (1), comprising converting a compound represented by general formula (3) in the presence of acid after reacting with an aniline derivative, or converting a compound represented by general formula (3) by reacting with an aniline derivative in the presence of an acid.

    摘要翻译: 提供了一种生产3,4-二氢异喹啉衍生物的有效方法及其有用的生产中间体。 提供一种制备由通式(1)表示的3,4-二氢异喹啉衍生物的方法,包括在与苯胺衍生物反应之后,在酸存在下将通式(3)表示的化合物转化,或将通式 式(3)与苯胺衍生物在酸的存在下反应。