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公开(公告)号:EP3492109A1
公开(公告)日:2019-06-05
申请号:EP18213451.0
申请日:2012-10-03
发明人: De Fougerolles, Antonin , Roy, Atanu , Schrum, Jason P. , Siddiqi, Suhaib , Hatala, Paul , Bancel, Stephane
摘要: The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them.
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公开(公告)号:EP3505176A1
公开(公告)日:2019-07-03
申请号:EP18203666.5
申请日:2013-03-09
发明人: Bancel, Stephane , Chakraborty, Tirtha , De Fougerolles, Antonin , Elbashir, Sayda M. , John, Matthias , Roy, Atanu , Whoriskey, Susan , Wood, Kristy M. , Hatala, Paul , Schrum, Jason P. , Ejebe, Kenechi , Ellsworth, Jeff Lynn , Guild, Justin
IPC分类号: A61K38/00 , C07K14/47 , C12N15/85 , A61K31/7115 , C12N9/88 , A61K9/00 , A61K9/14 , A61K9/16 , A61K9/127 , A61K31/7088 , C07K2/00 , C12N15/117 , C12P21/00 , A61K31/7105 , C12N15/88 , C12N15/00 , A61K38/17 , A61K9/51 , C07K14/495 , C12N9/02 , C07H21/02
摘要: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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公开(公告)号:EP3384938A1
公开(公告)日:2018-10-10
申请号:EP18159455.7
申请日:2012-09-11
CPC分类号: A61K48/005 , A61K45/06 , A61K48/0066 , C07K14/4723 , C12N2320/32
摘要: Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to kill or reduce the growth of viruses. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent viral infection, or to improve a subject's health or wellbeing.
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公开(公告)号:EP3520821A1
公开(公告)日:2019-08-07
申请号:EP18208097.8
申请日:2013-03-09
发明人: Bancel, Stephane , Chakraborty, Tirtha , De Fougerolles, Antonin , Elbashir, Sayda M. , John, Matthias , Roy, Atanu , Whoriskey, Susan , Wood, Kristy M. , Hatala, Paul , Schrum, Jason P. , Ejebe, Kenechi , Ellsworth, Jeff Lynn , Guild, Justin
IPC分类号: A61K48/00 , C07K14/47 , C12N15/85 , A61K31/7115 , C12N9/88 , A61K9/00 , A61K9/127 , A61K9/14 , A61K9/16 , A61K31/7088 , C07K2/00 , C12N15/117 , C12P21/00 , A61K31/7105 , C12N15/88 , C12N15/00 , A61K38/17
摘要: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
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