公开(公告)号：EP1984511A2

公开(公告)日：2008-10-29

申请号：EP07756875.6

申请日：2007-02-12

申请人： Monsanto Technology LLC

发明人： HECK, Gregory, R. ,  MUNYIKWA, Tichafa, R.I. ,  GOLEY, Jean, C. ,  ROBERTS, James, K. ,  JOHNSON, Scott, C. ,  VAUGHN, Ty, T.

IPC分类号： C12N15/82

CPC分类号： C12N15/113 ,  C12N15/111 ,  C12N15/8218 ,  C12N15/8286 ,  C12N2310/14 ,  C12N2320/10 ,  Y02A40/162

摘要： The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.