专利检索 ap:("Mylan Laboratories, Limited") AND inv:"GORE, Vinayak G" 第 1 页

1.

发明公开
CRYSTALLINE AND AMORPHOUS FORMS OF CARFILZOMIB 审中-公开

公开(公告)号：EP3411363A1

公开(公告)日：2018-12-12

申请号：EP16836116.0

申请日：2016-12-10

申请人： Mylan Laboratories, Limited

发明人： GORE, Vinayak G , SHUKLA, Vinay Kumar , SANGVIKAR, Yogesh , KOKANE, Dattatrey , GHARAT, Sushant

IPC分类号： C07D303/36 , A61K38/07 , A61K31/336 , A61K31/5375 , C07K5/10

CPC分类号： C07K5/1008 , A61K38/00 , A61K47/40 , C07B2200/13 , C07D303/36

摘要： The present disclosure provides crystalline carfilzomib form M1 and a process for the preparation thereof. Further disclosed are processes for the preparation of amorphous carfilzomib using crystalline form M1 as a starting material. The present disclosure also relates to an improved process for the preparation of carfilzomib.