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1.发明公开COMPOSITIONS CONTAINING ANTISENSE OLIGONUCLEOTIDE TO MICRO RNA 审中-公开WITH A反义寡核苷酸对去除微RNA COMPOSITIONS
公开(公告)号：EP2638912A4
公开(公告)日：2015-01-21
申请号：EP11840297
申请日：2011-11-10
IPC分类号： A61K31/7088 , A61K48/00 , A61P35/00 , C12N15/09 , C12N15/113
CPC分类号： C12N15/113 , A61K31/7088 , A61K48/00 , C12N2310/113 , C12N2310/141 , C12N2310/3231 , C12N2320/11 , C12N2330/31
摘要： Provided is a composition that contains an antisense oligonucleotide to a micro RNA and is capable of inhibiting the growth of cancer cells. The present invention, as one aspect, relates to a composition for suppressing the growth of human cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNAis selected from the group consisting of hsa-miR-133a, hsa-miR-133b, hsa-miR-346 and hsa-miR-361-3p. The present invention, as another aspect, relates to a composition for suppressing the growth of human head/neck cancer cells, the composition containing an antisense oligonucleotide to a micro RNA, wherein the micro RNA is selected from the group consisting of hsa-miR-92a, hsa-miR-133a, hsa-miR-133b, hsa-miR-139-5p, hsa-miR-197, hsa-miR-328, hsa-miR-346, hsa-miR-361-3p, hsa-miR-605, hsa-miR-766, hsa-miR-1228, hsa-miR-1252, hsa-miR-1260 and hsa-miR-1271.
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2.发明公开METHOD FOR ANALYZING CERVICAL LYMPH NODE METASTASIS, AND TUMOR MARKER FOR HEAD AND NECK CANCER 有权程序宫颈癌和肿瘤标志物的淋巴结转移癌分析头颈部肿瘤
公开(公告)号：EP2514835A4
公开(公告)日：2012-11-28
申请号：EP10839453
申请日：2010-12-22
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/158
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