公开(公告)号：EP3124507A4

公开(公告)日：2017-11-22

申请号：EP15768951

申请日：2015-03-23

申请人： NAT UNIV CORP YAMAGATA UNIV ,  NOF CORP

发明人： TANAKA MASARU ,  NAGASAWA ATSUSHI ,  TAKAOKA TOSHIAKI ,  AMAYA NAOYUKI

IPC分类号： C08F26/02 ,  A61L29/00 ,  A61L31/00 ,  C08L39/00

CPC分类号： C08F126/02 ,  A61L27/14 ,  A61L27/54 ,  A61L29/04 ,  A61L29/16 ,  A61L31/04 ,  A61L31/048 ,  A61L31/16 ,  C08F26/02 ,  C09D133/14 ,  C09D133/24

摘要： The present invention provides a polymer compound that can be expected to inhibit activation of a coagulation system, a complement system or a platelet system when brought into contact with in vivo tissue and/or blood since the compound is capable of containing intermediate water, and a composition and a device using the same. This problem is solved by a polymer compound containing a repeating unit represented by general formula (A), and used in contact with in vivo tissue and/or blood, in which in a process in which the polymer compound caused to contain water in a prescribed water content is cooled to -100°C and thereafter heated at a temperature rise rate of 5.0°C/min, a temperature region where exothermicity occurs is present in the range of -80°C or more and -25°C or less, and a temperature region where endothermicity occurs is present in the range of -25°C or more and lower than 0°C: wherein R represents a hydrocarbon group having 1 to 20 carbon atoms.

公开(公告)号：EP2987464A4

公开(公告)日：2016-12-21

申请号：EP14785083

申请日：2014-04-15

申请人： NAT UNIV CORP YAMAGATA UNIV ,  PIOLAX MEDICAL DEVICES INC

发明人： TANAKA MASARU ,  AOKI MAKIKO ,  SATO CHIKAKO ,  TOYOKAWA YOSHIHIDE ,  SHIRAKAWA KYOSUKE

IPC分类号： A61F2/04 ,  A61L31/00

CPC分类号： A61F2/04 ,  A61F2/07 ,  A61F2/848 ,  A61F2/915 ,  A61F2002/041 ,  A61F2002/072 ,  A61F2002/9155 ,  A61F2002/91575 ,  A61L31/10 ,  C08L33/14

摘要： Provided are a stent to be placed in the bile duct and a process for producing the stent, the stent hollow being less apt to be blocked even when the stent is placed in the bile duct for a long period. This stent (10) to be placed in the bile duct is either a stent (10) that comprises a stent base (20) constituted of a cylindrical metal mesh tube and a covering member (30) with which the outer periphery and/or inner periphery of the stent base (20) has been covered or a stent (10") constituted of a cylindrical resin tube (20'), the inner peripheral surface of the stent having been coated with a resin layer (40) with resistance to sludge formation that comprises a polymer obtained by polymerizing 2-methoxyethyl acrylate. This stent to be placed in the bile duct is produced by applying a coating fluid that contains 0.1-0.5 mass% polymer obtained by polymerizing 2-methoxyethyl acrylate, to the inner peripheral surface of a stent, thereby coating the inner peripheral surface of the stent with a resin layer having resistance to sludge formation and comprising the polymer.