公开(公告)号：EP0912528B1

公开(公告)日：2003-05-28

申请号：EP97922127.2

申请日：1997-05-21

申请人： NISSAN CHEMICAL INDUSTRIES, LIMITED

发明人： FUKUDA, Kenzo, Nissan Chem. Ind., Ltd. Onoda Kojo ,  HATANAKA,Masataka, Nissan Chem.Ind.,Ltd.Onoda Koyo ,  MAKABE, Takahiro, Nissan Chem.Ind.,Ltd. Onoda Kojo ,  ISHII, Kenichi, Nissan Chem. Ind., Ltd. Onoda kojo

IPC分类号： C07D241/44

CPC分类号： C07D405/12 ,  C07B2200/07 ,  C07D241/44

摘要： A process for producing D(+)-2-[4-(6-chloro-2-quinoxalyloxy)phenoxy]propionic acid, which comprises reacting an alkali metal salt of 4-(6-chloro-2-quinoxalyloxy)phenol with an alkali metal salt of L-2-chloropropionic acid in an aromatic hydrocarbon solvent in the presence of an aprotic polar solvent to obtain an alkali metal salt of D(+)-2-[4-(6-chloro-2-quinoxalyloxy)phenoxy]propionic acid, and treating it with an acid.