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    Percutaneous absorption-type pharmaceutical preparation using a metal chloride, preferably sodium chloride, for preventing cohesive failure
    1.
    发明公开
    Percutaneous absorption-type pharmaceutical preparation using a metal chloride, preferably sodium chloride, for preventing cohesive failure 有权
    使用金属氯化物，优选氯化钠，用于防止粘合的弱点用于经皮吸收的药物组合物

    公开(公告)号：EP1731143A1

    公开(公告)日：2006-12-13

    申请号：EP06011513.6

    申请日：2006-06-02

    申请人： NITTO DENKO CORPORATION ,  Fujimoto Co., Ltd.

    发明人： Inosaka, Keigo ,  Muraoka, Takateru ,  Iwao, Yoshihiro ,  Takada, Akio ,  Tsuda, Toshinobu ,  Sekiya, Junichi

    IPC分类号： A61K9/70 ,  A61K31/135 ,  A61K47/02

    CPC分类号： A61K31/135 ,  A61K9/7061 ,  A61K47/02

    摘要： A stable percutaneous absorption-type pharmaceutical preparation for percutaneous administration of selegiline or selegiline hydrochloride, which does not suffer a decrease in the cohesive force of the adhesive layer therein even in the presence of sweat components due to perspiration during wear and which is free from cohesive failure and resultant adhesive remaining when stripped off, is provided. A percutaneous absorption-type pharmaceutical preparation which comprises: a support; and an adhesive layer containing a metal chloride, an adhesive and at least one of (-)-(R)-N,α-dimethyl-N-2-propynylphenethylamine and its hydrochloride, wherein the adhesive layer is subjected to a crosslinking treatment.

    摘要翻译： 用于司来吉兰或司来吉兰盐酸盐，经皮给药的稳定的经皮吸收型药物制剂，其不会遭受以其中即使在汗液组分存在的粘合剂层的凝聚力下降，由于在穿着期间出汗和所有这些是从内聚自由 失败和所得的粘合剂残留时剥离，被提供。 其包括经皮吸收型药物制剂：载体; 和粘合剂层含有金属氯化物，至少一种粘合剂和以（ - ） - （R）-N，±二甲基-N-2-丙炔基苯乙胺和其盐酸盐，worin粘合剂层进行交联处理。

    Percutaneous absorption-type pharmaceutical preparation using a metal chloride, preferably sodium chloride, for preventing cohesive failure
    5.
    发明公开
    Percutaneous absorption-type pharmaceutical preparation using a metal chloride, preferably sodium chloride, for preventing cohesive failure 有权
    使用金属氯化物，优选氯化钠，用于防止粘合的弱点用于经皮吸收的药物组合物

    公开(公告)号：EP1733719A1

    公开(公告)日：2006-12-20

    申请号：EP06011300.8

    申请日：2006-05-31

    申请人： NITTO DENKO CORPORATION

    发明人： Inosaka, Keigo ,  Sekiya, Junichi ,  Takada, Akio ,  Tsuda, Toshinobu

    IPC分类号： A61K9/70 ,  A61K31/275 ,  A61K47/02

    CPC分类号： A61K31/275 ,  A61K9/7061 ,  A61K47/02

    摘要： A stable percutaneous absorption-type pharmaceutical preparation for percutaneous administration of drugs except for selegiline and selegiline hydrochloride, which does not suffer a decrease in the cohesive force of the adhesive layer therein even in the presence of sweat components due to perspiration during wear and which is free from cohesive failure and resultant adhesive remaining when stripped off. A percutaneous absorption-type pharmaceutical preparation which comprises: a support; and an adhesive layer containing an adhesive, a metal chloride and a percutaneously-absorptive drug except for selegiline and selegiline hydrochloride, wherein the adhesive layer is subjected to a crosslinking treatment.

    摘要翻译： 对于除司来吉兰和司来吉兰盐酸盐，其不遭受在该粘合剂层的。其中，即使在汗液组分存在的凝聚力下降，由于穿戴期间汗水的药物经皮给药和稳定的经皮吸收型药物制剂的所有其 从内聚破坏和粘合剂剩余的合力自由当剥离，其包括经皮吸收型药物制剂：支撑;. 和粘合剂层含的粘合剂，金属氯化物和除了司来吉兰和司来吉兰盐酸盐的经皮吸收药物，worin粘合剂层进行交联处理。