公开(公告)号：EP2089515A4

公开(公告)日：2011-02-23

申请号：EP07864554

申请日：2007-11-16

申请人： NOVAVAX INC

发明人： SMITH GALE ,  PUSHKO PETER ,  MASSARE MIKE ,  WU YINGYUN ,  MAHMOOD KUTUB

IPC分类号： C12N7/00

CPC分类号： A61K39/155 ,  A61K39/12 ,  A61K2039/5258 ,  C07K14/005 ,  C12N2760/18522 ,  C12N2760/18523 ,  C12N2760/18534

摘要： The present invention discloses and claims virus like particles (VLPs) that express and/or contains RSV proteins. The invention includes vector constructs comprising said proteins, cells comprising said constructs, formulations and vaccines comprising VLPs of the inventions. The invention also includes methods of making and administrating VLPs to vertebrates, including methods of inducing immunity to infections, including RSV.

摘要翻译： 本发明公开并要求表达和/或含有RSV蛋白的病毒样颗粒（VLPs）。 本发明包括包含所述蛋白质的载体构建体，包含所述构建体的细胞，制剂和包含本发明的VLP的疫苗。 本发明还包括制备和施用VLP到脊椎动物的方法，包括诱导感染免疫的方法，包括RSV。