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1.发明授权PURINE-2,6-DIONES WHICH ARE INHIBITORS OF THE ENZYME DIPEPTIDYL PEPTIDASE IV (DPP-IV) 有权嘌呤-2,6-二酮酶二肽基肽酶IV的ALS抑制剂（DPP-IV）
公开(公告)号：EP1301187B1
公开(公告)日：2005-07-06
申请号：EP01947211.7
申请日：2001-07-04
申请人： NOVO NORDISK A/S
发明人： KANSTRUP, Anders, Bendtz , CHRISTIANSEN, Lise, Brown , LUNDBECK, Jane, Marie , SAMS, Christian, K. , KRISTIANSEN, Marit
IPC分类号： A61K31/522 , C07D473/04 , C07D473/06 , C07D473/08
CPC分类号： C07D473/04 , C07D473/08
摘要： The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity, as well as methods for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity.
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2.发明公开HETEROCYCLIC COMPOUNDS, WHICH ARE INHIBITORS OF THE ENZYME DPP-IV 有权嘌呤-2,6-二酮酶二肽基肽酶IV的ALS抑制剂（DPP-IV）
公开(公告)号：EP1301187A2
公开(公告)日：2003-04-16
申请号：EP01947211.7
申请日：2001-07-04
申请人： NOVO NORDISK A/S
发明人： KANSTRUP, Anders, Bendtz , CHRISTIANSEN, Lise, Brown , LUNDBECK, Jane, Marie , SAMS, Christian, K. , KRISTIANSEN, Marit
IPC分类号： A61K31/522 , C07D473/04 , C07D473/06 , C07D473/08
CPC分类号： C07D473/04 , C07D473/08
摘要： The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity, as well as methods for treating diseases that are associated with proteins which are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity.
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