专利检索 ap:("National Cancer Center" OR "RIKEN") AND inv:"FUKUOKA, Shota" 第 1 页

1.

发明公开
ENHANCEMENT OF ANTITUMOR EFFECT OF IMMUNE CHECKPOINT INHIBITOR THROUGH ADMINISTRATION OF INTESTINAL RUMINOCOCCACEAE BACTERIUM 审中-公开

公开(公告)号：EP4223868A1

公开(公告)日：2023-08-09

申请号：EP21875721.9

申请日：2021-09-29

申请人： National Cancer Center , RIKEN

发明人： NISHIKAWA, Hiroyoshi , FUKUOKA, Shota , BENNO, Yoshimi , SHIGENO, Yuko

IPC分类号： C12N1/20 , A61K35/741 , A61K39/395 , A61K45/00 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/04 , A61P43/00 , C12N15/11 , C12Q1/6869

摘要： To provide a pharmaceutical composition capable of enhancing the effect of an immune checkpoint inhibitor against tumor or cancer in a subject. Provided is a pharmaceutical composition that comprises bacterial cells, a culture supernatant, a metabolite, and/or a bacterial cell extract of Ruminococcaceae enterobacterium, and is administered in combination with an immune checkpoint inhibitor.