公开(公告)号：EP2438926A1

公开(公告)日：2012-04-11

申请号：EP10783165.3

申请日：2010-06-04

申请人： National Institute of Advanced Industrial Science and Technology ,  National Institute of Infectious Diseases ,  M Bio Technology Inc.

发明人： MATSUDA, Kazuhiro ,  ICHIYAMA, Koji ,  MATSUDA, Sachie ,  SASAKI, Yuko ,  ARAKAWA, Yoshichika ,  HARASAWA, Ryo ,  NISHIDA, Yoshihiro ,  KATAYAMA, Norio ,  ENDO, Yasuo ,  NOMURA, Nobuo

IPC分类号： A61K39/00 ,  A61K9/127 ,  A61K39/145 ,  A61K47/24 ,  A61K47/28 ,  A61P11/00 ,  A61P11/06 ,  A61P19/02 ,  A61P29/00 ,  A61P31/04 ,  A61P31/16

CPC分类号： A61K39/0241 ,  A61K9/127 ,  A61K9/1272 ,  A61K39/12 ,  A61K39/145 ,  A61K39/39 ,  A61K2039/55555 ,  A61K2039/55594 ,  Y02A50/403

摘要： Disclosed is a vaccine which has a high therapeutic effect on mycoplasma infection and is highly safe. For the purpose of developing effective therapeutic methods for mycoplasma infection, mycoplasma-mimic particles which are effective as a vaccine for mycoplasma infection are provided, and also provided are bacterium-mimic particles including common bacteria. Bacterium-mimic particles such as mycoplasma-mimic particles can be provided by producing liposome particles in which a lipid antigen specific to a pathogenic bacterium such as mycoplasma is contained as a liposome-constituting lipid component. The administration of the mycoplasma-mimic particles enables the induction of a potent immunological activity in living bodies. The mycoplasma-mimic particles can be used as an excellent vaccine for the prevention or treatment of mycoplasma infection.

公开(公告)号：EP2438926B1

公开(公告)日：2016-03-23

申请号：EP10783165.3

申请日：2010-06-04

申请人： M Bio Technology Inc. ,  National Institute of Infectious Diseases

发明人： MATSUDA, Kazuhiro ,  ICHIYAMA, Koji ,  MATSUDA, Sachie ,  SASAKI, Yuko ,  ARAKAWA, Yoshichika ,  HARASAWA, Ryo ,  NISHIDA, Yoshihiro ,  KATAYAMA, Norio ,  ENDO, Yasuo ,  NOMURA, Nobuo

IPC分类号： A61K39/00 ,  A61K9/127 ,  A61K39/145 ,  A61K47/24 ,  A61K47/28 ,  A61P11/00 ,  A61P11/06 ,  A61P19/02 ,  A61P29/00 ,  A61P31/04 ,  A61P31/16 ,  A61K39/39

CPC分类号： A61K39/0241 ,  A61K9/127 ,  A61K9/1272 ,  A61K39/12 ,  A61K39/145 ,  A61K39/39 ,  A61K2039/55555 ,  A61K2039/55594 ,  Y02A50/403

摘要： Disclosed is a vaccine which has a high therapeutic effect on mycoplasma infection and is highly safe. For the purpose of developing effective therapeutic methods for mycoplasma infection, mycoplasma-mimic particles which are effective as a vaccine for mycoplasma infection are provided, and also provided are bacterium-mimic particles including common bacteria. Bacterium-mimic particles such as mycoplasma-mimic particles can be provided by producing liposome particles in which a lipid antigen specific to a pathogenic bacterium such as mycoplasma is contained as a liposome-constituting lipid component. The administration of the mycoplasma-mimic particles enables the induction of a potent immunological activity in living bodies. The mycoplasma-mimic particles can be used as an excellent vaccine for the prevention or treatment of mycoplasma infection.