公开(公告)号：EP2489735A1

公开(公告)日：2012-08-22

申请号：EP10823461.8

申请日：2010-10-15

申请人： National University Corporation Tokyo University of Marine Science and Technology

发明人： AOKI Takashi ,  HIRONO Ikuo

IPC分类号： C12N15/09 ,  A61K31/7088 ,  A61P31/12 ,  G01N33/543 ,  G01N33/569

CPC分类号： A61K31/7088 ,  A61K9/0019 ,  A61K38/00 ,  C07K14/005 ,  C12N2760/20011 ,  C12N2760/20022 ,  G01N33/56983 ,  G01N2333/145

摘要： Disclosed are: a pharmaceutical and a method capable of preventing and treating VHSV infection; a method for removing VHSV from a particular water area; and a method and a kit for simply detecting VHSV with high sensitivity. Specifically disclosed are: a VHSV-binding aptamer having the activity of binding to VHSV and/or a polypeptide expressed in the virus and suppressing the VHSV infection of a host; and a method for detecting VHSV and/or a polypeptide expressed in the virus, using the VHSV-binding aptamer.

摘要翻译： 公开的是：能够预防和治疗VHSV感染的药物和方法; 从特定水域去除VHSV的方法; 以及用于简单地以高灵敏度检测VHSV的方法和试剂盒。 具体公开的是具有与VHSV结合的活性的VHSV结合适体和/或病毒中表达的多肽并抑制宿主的VHSV感染; 以及使用VHSV结合适体检测病毒中表达的VHSV和/或多肽的方法。

公开(公告)号：EP2489735A9

公开(公告)日：2013-03-13

申请号：EP10823461.8

申请日：2010-10-15

申请人： National University Corporation Tokyo University of Marine Science and Technology

发明人： AOKI Takashi ,  HIRONO Ikuo

IPC分类号： C12N15/09 ,  A61K31/7088 ,  A61P31/12 ,  G01N33/543 ,  G01N33/569

CPC分类号： A61K31/7088 ,  A61K9/0019 ,  A61K38/00 ,  C07K14/005 ,  C12N2760/20011 ,  C12N2760/20022 ,  G01N33/56983 ,  G01N2333/145

摘要： Disclosed are: a pharmaceutical and a method capable of preventing and treating VHSV infection; a method for removing VHSV from a particular water area; and a method and a kit for simply detecting VHSV with high sensitivity. Specifically disclosed are: a VHSV-binding aptamer having the activity of binding to VHSV and/or a polypeptide expressed in the virus and suppressing the VHSV infection of a host; and a method for detecting VHSV and/or a polypeptide expressed in the virus, using the VHSV-binding aptamer.

摘要翻译： 公开了能够预防和治疗VHSV感染的药物和方法; 从特定水域去除VHSV的方法; 以及用于以高灵敏度简单检测VHSV的方法和试剂盒。 具体公开了：具有结合VHSV和/或病毒中表达的多肽并抑制宿主VHSV感染的活性的VHSV结合适体; 以及使用VHSV结合适体检测病毒中表达的VHSV和/或多肽的方法。