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公开(公告)号:EP2396345A1
公开(公告)日:2011-12-21
申请号:EP10704016.4
申请日:2010-02-12
发明人: BIKKER, Floris Jacob , VAN DIJK, Albert , MARS-GROENENDIJK, Rosalia , VELDHUIZEN, Edwin Johannes Adrianus , VAN DER KLEIJ, Desiree , HAAGSMAN, Hendrik , MOLHOEK, Elisabeth Margarita
IPC分类号: C07K14/465 , A61K38/17 , A61P31/04
CPC分类号: C07K14/465 , A61K39/39 , A61K2039/55516 , C07K7/08 , C07K14/47
摘要: The invention concerns derivatives of CMAP27, which have a good antimicrobial activity and a low haemolytic activity as compared to the wild- type CMAP27 peptide. These derivatives can be used for antibiotic therapy or in a bacteriocidal composition. Further comprised in the invention is the use of CMAP27 and/or its derivatives as adjuvant.