公开(公告)号：EP2120932A1

公开(公告)日：2009-11-25

申请号：EP07857632.9

申请日：2007-12-14

申请人： Nerviano Medical Sciences S.r.l.

发明人： BANDIERA, Tiziano ,  LOMBARDI BORGIA, Andrea ,  NESI, Marcella ,  PERRONE, Ettore ,  BOSSI, Roberto ,  POLUCCI, Paolo

IPC分类号： A61K31/4162 ,  A61P35/00

CPC分类号： C07D231/56 ,  C07D401/12 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D471/04

摘要： Substituted indazole derivativesof formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a dysregulated protein kinase activity, like cancer formula (I).

公开(公告)号：EP2120932B1

公开(公告)日：2014-07-09

申请号：EP07857632.9

申请日：2007-12-14

申请人： Nerviano Medical Sciences S.r.l.

发明人： BANDIERA, Tiziano ,  LOMBARDI BORGIA, Andrea ,  NESI, Marcella ,  PERRONE, Ettore ,  BOSSI, Roberto ,  POLUCCI, Paolo

IPC分类号： A61K31/4162 ,  A61P35/00

CPC分类号： C07D231/56 ,  C07D401/12 ,  C07D403/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D471/04