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公开(公告)号:EP2906205A1
公开(公告)日:2015-08-19
申请号:EP13780276.5
申请日:2013-10-09
发明人: DAVE, Rajesh, N. , TO, Daniel , CAPECE, Maxx
CPC分类号: A61K9/5042 , A61K9/5063 , A61K9/5073 , A61K9/5089 , A61K35/00
摘要: The present invention is a solventless method of producing polymer coated active pharmaceutical ingredient that is taste-masked and may be released in relatively short time. It employs high energy vibrations or acoustic mixing of API particles, water soluble coating material particles and hydrophobic polymer particles, with or without use of other pharmaceutically relevant powders as media. Additionally the method is capable of producing individually coated drug particles without agglomeration or the long drying times associated with solvent based coating methods.
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公开(公告)号:EP2906205B1
公开(公告)日:2018-06-13
申请号:EP13780276.5
申请日:2013-10-09
发明人: DAVE, Rajesh, N. , TO, Daniel , CAPECE, Maxx
CPC分类号: A61K9/5042 , A61K9/5063 , A61K9/5073 , A61K9/5089 , A61K35/00
摘要: The present invention is a solventless method of producing polymer coated active pharmaceutical ingredient that is taste-masked and may be released in relatively short time. It employs high energy vibrations or acoustic mixing of API particles, water soluble coating material particles and hydrophobic polymer particles, with or without use of other pharmaceutically relevant powders as media. Additionally the method is capable of producing individually coated drug particles without agglomeration or the long drying times associated with solvent based coating methods.
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