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    CRYSTALLINE GLUCOSAMINE SULPHATE METAL SALTS AND PROCESSES FOR PREPARING THE SAME
    1.
    发明公开
    CRYSTALLINE GLUCOSAMINE SULPHATE METAL SALTS AND PROCESSES FOR PREPARING THE SAME 有权
    结晶葡萄糖胺硫酸盐金属盐及其制备方法

    公开(公告)号：EP1347986A2

    公开(公告)日：2003-10-01

    申请号：EP01998306.3

    申请日：2001-12-03

    申请人： Nicholas Piramal India Limited

    发明人： MUKHOPADHYAY, Triptikumar ,  BHAT, Ravi Gajanan ,  SREEKUMAR, E. S.

    IPC分类号： C07H5/04 ,  C07H5/06 ,  C08B37/00 ,  A01N43/04 ,  A61K31/20

    CPC分类号： C07H5/06

    摘要： The present invention relates to novel crystalline glucosamine sulphate metal salts for use in the treatment of acute and chronic forms of rheumatic and arthritic diseases and of all the pathological conditions originating from metabolic disorders of the osteo-articular tissues. More particularly, the present invention relates to novel crystalline glucosamine sulphate metal salts having low metal content wherein the metal may be either sodium or potassium. The present invention further relates to a solution-based and a solvent-free process for the preparation of the novel crystalline glucosamine sulphate metal salts having low metal content and to pharmaceutical compositions comprising the novel crystalline glucosamine sulphate metal salts having low metal content.

    摘要翻译： 本发明涉及新的结晶葡糖胺硫酸盐金属盐，用于治疗急性和慢性形式的风湿病和关节炎疾病以及所有源自骨关节组织代谢紊乱的病理状态。 更具体地说，本发明涉及具有低金属含量的新型结晶葡糖胺硫酸盐金属盐，其中金属可以是钠或钾。 本发明进一步涉及用于制备具有低金属含量的新型结晶葡糖胺硫酸盐金属盐的基于溶液的和无溶剂的方法，并涉及包含具有低金属含量的新型结晶葡糖胺硫酸盐金属盐的药物组合物。