专利检索 ap:("Nicox Ophthalmics, Inc.") AND inv:"BOYER, José L." 第 1 页

1.

发明公开
PROCESS FOR THE PREPARATION OF STERILE OPHTHALMIC AQUEOUS FLUTICASONE PROPIONATE FORM A NANOCRYSTALS SUSPENSIONS 审中-公开

公开(公告)号：EP3769753A1

公开(公告)日：2021-01-27

申请号：EP20186965.8

申请日：2020-07-21

申请人： Nicox Ophthalmics, Inc.

发明人： BUKOWSKI, Jean-Michel , NADKARNI, Akshay , BOYER, José L. , DUQUESROIX-CHAKROUN, Brigitte , NAVRATIL, Tomas

IPC分类号： A61K9/14 , A61K9/10 , A61K47/02 , A61K47/10 , A61K31/56 , A61P27/00 , C07J31/00 , C07J71/00

摘要： The present invention relates to an improved process of manufacturing sterile topical ophthalmic aqueous nanosuspensions of nanocrystals of fluticasone propionate Form A. The sterile topical ophthalmic nanosuspensions are useful in the treatment of eye inflammation conditions such as blepharitis, posterior blepharitis, Meibomian gland dysfunction and dry eye through topical administration of said nanosuspensions to eyelids, eyelashes and eyelid margin.