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1.发明公开
公开(公告)号：EP4276207A1
公开(公告)日：2023-11-15
申请号：EP21917755.7
申请日：2021-12-27
发明人： HONDA, Yoshio , ITO, Taku , ICHINOSE, Jun , NAGATSU, Kotaro , SUZUKI, Hisashi
摘要： One aspect of the present invention relates to a recovery method of 226 Ra, and the recovery method of 226 Ra includes a step (A1) of immersing a solid-state 226 Ra-containing substance and a carrier having a function of adsorbing 226 Ra ions in a processing solution, and then irradiating the processing solution with ultrasonic waves.
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2.发明公开
公开(公告)号：EP4276855A1
公开(公告)日：2023-11-15
申请号：EP22736746.3
申请日：2022-01-05
发明人： HONDA, Yoshio , ITO, Taku , ICHINOSE, Jun , ICHIKAWA, Hiroaki , IMAI, Tomoyuki , NAGATSU, Kotaro , SUZUKI, Hisashi
IPC分类号： G21G4/08
摘要： An aspect of the present invention relates to a method for producing an 225 Ac solution or a method for producing a medicine using the solution. The method for producing an 225 Ac solution includes a step of irradiating a 226 Ra target with particles to generate two or more actinium radioisotopes (Ac) including at least 225 Ac, a step of dissolving the 226 Ra target after the aforementioned step to obtain a solution (1) that contains 226 Ra and Ac, a step of separating 226 Ra and Ac contained in the solution (1) to obtain a solution (2) that has a higher Ac concentration than the solution (1), a step of allowing Ac contained in the solution (2) other than 225 Ac to decay to obtain a solution (3) containing radium isotopes (Ra) resulting from decay, and a step of separating Ra and Ac contained in the solution (3) to obtain a solution (4) that has a higher 225 Ac concentration than the solution (3), and the solution (4) is used to produce a medicine that contains, as an active ingredient, a conjugate between a chelating agent that has formed a complex with 225 Ac, and an Nd2 antibody or a targeting agent (excluding Nd2 antibodies).
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