公开(公告)号：EP1284653B1

公开(公告)日：2007-11-28

申请号：EP01935124.6

申请日：2001-05-08

申请人： Nitromed, Inc.

发明人： MAREK, Przemyslaw, A. ,  TROCHA, Andrzej, M.

IPC分类号： A61B6/00 ,  A61K49/00 ,  A61K31/42 ,  A61B5/00 ,  A61P15/00

CPC分类号： A61B5/4368 ,  A61B5/015 ,  A61K49/0004 ,  Y10S514/929

摘要： The present invention describes rapid non-invasive methods for measuring vasodilation or changes in blood flow in a patient following administration of at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one vasoactive agent. The method comprises administration of at least one compound to the patient followed by monitoring the temperature change of an area of interest using infrared thermography.

公开(公告)号：EP1284653A2

公开(公告)日：2003-02-26

申请号：EP01935124.6

申请日：2001-05-08

申请人： Nitromed, Inc.

发明人： MAREK, Przemyslaw, A. ,  TROCHA, Andrzej, M.

IPC分类号： A61B6/00

CPC分类号： A61B5/4368 ,  A61B5/015 ,  A61K49/0004 ,  Y10S514/929

摘要： The present invention describes rapid non-invasive methods for measuring vasodilation or changes in blood flow in a patient following administration of at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one vasoactive agent. The method comprises administration of at least one compound to the patient followed by monitoring the temperature change of an area of interest using infrared thermography.