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公开(公告)号:EP2805712A1
公开(公告)日:2014-11-26
申请号:EP14001800.3
申请日:2005-05-17
发明人: Ashley, Adrian. , Lamb, Paul. , Mcdonald, Donald. , Miller, John. , Oliver, Martin.J. , Pollard, Mathew.
IPC分类号: A61K9/10
CPC分类号: A61K9/1682 , A61K31/56 , A61K31/573 , A61K31/58 , A61L2/0011 , A61L2/0023 , C07J5/00
摘要: The present invention provides a method for the sterilization of a labile glucocorticosteroid, which method comprises heat-treating by moist heat the labile glucocorticosteroid in the form of a suspension for a sterilizing-effective time. The methods and compositions according to the invention are useful as therapeutic tools to prevent, reverse, and/or reduce the symptoms of allergic and/or inflammatory conditions in a mammalian patient. The invention also provides methods and compositions, which may be manipulated and fine-tuned to fit the condition(s) to be treated while producing fewer side effects.
摘要翻译: 本发明提供了一种不稳定的糖皮质激素的灭菌方法,该方法包括通过湿热对处于悬浮液形式的不稳定的糖皮质激素进行热消毒以达到消毒有效的时间。 根据本发明的方法和组合物可用作预防,逆转和/或减轻哺乳动物患者中过敏性和/或炎性病症症状的治疗工具。 本发明还提供了方法和组合物,其可以被操作并被微调以适应待治疗的病症,同时产生更少的副作用。
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公开(公告)号:EP2805712B1
公开(公告)日:2018-02-28
申请号:EP14001800.3
申请日:2005-05-17
发明人: Ashley, Adrian. , Lamb, Paul. , Mcdonald, Donald. , Miller, John. , Oliver, Martin.J. , Pollard, Mathew.
IPC分类号: A61K9/10
CPC分类号: A61K9/1682 , A61K31/56 , A61K31/573 , A61K31/58 , A61L2/0011 , A61L2/0023 , C07J5/00
摘要: The present invention provides a method for the sterilization of a labile glucocorticosteroid, which method comprises heat-treating by moist heat the labile glucocorticosteroid in the form of a suspension for a sterilizing-effective time. The methods and compositions according to the invention are useful as therapeutic tools to prevent, reverse, and/or reduce the symptoms of allergic and/or inflammatory conditions in a mammalian patient. The invention also provides methods and compositions, which may be manipulated and fine-tuned to fit the condition(s) to be treated while producing fewer side effects.
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