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1.发明公开Use of collismycin and derivatives thereof as oxidative stress inhibitors 审中-公开Verwendung von Collismycin und Derivaten davon als oxidative Stresshemmer
公开(公告)号：EP2444121A1
公开(公告)日：2012-04-25
申请号：EP12151913.6
申请日：2006-07-28
发明人： Martínez Gil, Ana , Castro Morera, Ana , Alonso Cascón, Mercedes , Sánchez Quesada, Jorge , Usán Egea, Paola , Medina Padilla, Miguel , García Palomero, Esther , Pérez Baz, Julia , Fernández Chimeno, Rosa Isabel , Fernández Medarde, Antonio , Cañedo Hernández, Librada María , Romero Millán, Francisco
CPC分类号： A61K31/44
摘要： The present invention relates to the use of Collismycin and derivatives thereof as inhibitors of oxidative stress in cells and their use for the preparation of medicaments for the treatment and/or prevention of oxidative stress-induced diseases or conditions, especially neurodegenerative diseases, such as Alzheimer's Disease and Parkinson's Disease.
摘要翻译： 本发明涉及Collismycin及其衍生物作为细胞氧化应激抑制剂及其在制备用于治疗和/或预防氧化应激诱发的疾病或病症，特别是神经变性疾病如阿尔茨海默病的药物中的应用。 疾病和帕金森病。
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2.发明公开Use of collismycin and derivatives thereof as oxidative stress inhibitors 审中-公开Verwendung von Collismycin und deren Derivaten als Inhibitoren des oxidativen Stress
公开(公告)号：EP1749552A1
公开(公告)日：2007-02-07
申请号：EP05380175.9
申请日：2005-07-29
发明人： Martinez Gil, Ana , Usán Egea, Paola , Medina Padilla, Miguel , Garcia Palomero, Esther , Pérez Baz, Julia , Fernández Chimeno, Rosa Isabel , Fernández Medarde, Antonio
CPC分类号： A61K31/44
摘要： The present invention relates to the use of Collismycin and derivatives thereof as inhibitors of oxidative stress in cells and their use for the preparation of medicaments for the treatment of oxidative stress-induced diseases or conditions, specially neurodegenerative diseases, such as Alzheimer's Disease and Parkinson's Disease.
摘要翻译： 本发明涉及Collicycin及其衍生物作为细胞氧化应激抑制剂及其用于制备用于治疗氧化应激诱发的疾病或病症，特别是神经变性疾病如阿尔茨海默病和帕金森病的药物的用途 。
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3.发明公开[1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases 审中-公开[1,10] -Phenanthrolin-Derivate zur Behandlung neurodegenerativer oderhämatologischerErkrankungen
公开(公告)号：EP2002863A1
公开(公告)日：2008-12-17
申请号：EP07380167.2
申请日：2007-06-11
申请人： NOSCIRA, S.A.
发明人： Martínez Gil, Ana , Castro Morera, Ana , Medina Padilla, Miguel , Sánchez-Quesada, Jorge , Alonso Cascón, Mercedes , Rubio Arrieta, Laura , García Palomero, Esther , Usán Egea, Paola
IPC分类号： A61P25/16 , A61P25/28 , A61P3/10 , A61K31/4745 , C07D471/04
CPC分类号： C07D471/04
摘要： The present invention relates to a new family of [1,10]-phenantroline derivatives of formula (I), which are useful for the treatment or profilaxis of a neurodegenerative or haematological disease or condition, their use as a medicament, especially for treating a treatment neurodegenerative or haematological disease or condition, and a pharmaceutical composition comprising the compounds.
摘要翻译： 本发明涉及式（I）的[1,10] - phen啉衍生物的新家族，它们可用于治疗或表现神经变性或血液病学疾病或病症，其用作药物，特别是用于治疗 治疗神经变性或血液病或病症，以及包含该化合物的药物组合物。
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