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公开(公告)号:EP3010936A2
公开(公告)日:2016-04-27
申请号:EP14738994.4
申请日:2014-06-20
申请人: Novartis AG
发明人: DOLE, William , TRAUGER, John , TANG, Yuting , NEUGEBAUER, Julia , SCHMID, Annika , HELDWEIN, Kurt , BROGDON, Jennifer
IPC分类号: C07K16/28
CPC分类号: C07K16/2851 , A61K39/3955 , A61K2039/505 , A61P9/04 , A61P9/08 , A61P9/10 , A61P9/12 , C07K14/33 , C07K14/4726 , C07K16/28 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The present invention relates to monoclonal antibodies binding to human lectin-like oxidized LDL (low density lipoprotein) receptor 1 (hereinafter, sometimes referred to as “LOX-1”), and pharmaceutical compositions and methods of treatment comprising the same.
摘要翻译: 本发明涉及与人凝集素样氧化LDL(低密度脂蛋白)受体1(以下有时称为“LOX-1”)结合的单克隆抗体,以及包含其的药物组合物和治疗方法。