公开(公告)号：EP2122390B1

公开(公告)日：2011-11-02

申请号：EP08708741.7

申请日：2008-02-06

申请人： Novartis AG

发明人： GONZALEZ FERREIRO, Maria ,  KRÖHNE, Lutz ,  MUELLER, Achim ,  NIKOLAUS, Katharina ,  VOIGT, Andreas

IPC分类号： G02B1/04

CPC分类号： G02B1/043 ,  C08J7/04 ,  Y10T428/31511

摘要： A method for making a contact lens comprising a core material and a coating thereon, the method comprising the steps of : (a) providing the core material; (b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic material is a reaction product of : (i) an epoxide of formula (I) wherein X equals bromo, chloro, iodo, or cyano, and R1, R2, R3, R4, independently of one another, are selected from the group consisting of hydrogen, linear or branched C1C6-alkyl, and linear or branched C1C6-alkyl which is substituted with halogen, and (ii) a polymer having repeating units comprising one or more secondary or tertiary amine group(s); (c) applying one or more layers of a polyanionic material; and (d) cross-linking the layers of polyelectrolytes formed by steps (b) and (c). The contact lenses obtainable by the method of the invention have desirable characteristics regarding adherence to the core material, durability, hydrophilicity, and wettability.

公开(公告)号：EP2122390A1

公开(公告)日：2009-11-25

申请号：EP08708741.7

申请日：2008-02-06

申请人： Novartis AG

发明人： GONZALEZ FERREIRO, Maria ,  KRÖHNE, Lutz ,  MUELLER, Achim ,  SCHMID, Katharina ,  VOIGT, Andreas

IPC分类号： G02B1/04

CPC分类号： G02B1/043 ,  C08J7/04 ,  Y10T428/31511

摘要： A method for making a contact lens comprising a core material and a coating thereon, the method comprising the steps of : (a) providing the core material; (b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic material is a reaction product of : (i) an epoxide of formula (I) wherein X equals bromo, chloro, iodo, or cyano, and R1, R2, R3, R4, independently of one another, are selected from the group consisting of hydrogen, linear or branched C1C6-alkyl, and linear or branched C1C6-alkyl which is substituted with halogen, and (ii) a polymer having repeating units comprising one or more secondary or tertiary amine group(s); (c) applying one or more layers of a polyanionic material; and (d) cross-linking the layers of polyelectrolytes formed by steps (b) and (c). The contact lenses obtainable by the method of the invention have desirable characteristics regarding adherence to the core material, durability, hydrophilicity, and wettability.