公开(公告)号：EP1235566A2

公开(公告)日：2002-09-04

申请号：EP00990671.0

申请日：2000-12-07

申请人： Novartis AG ,  Novartis-Erfindungen Verwaltungsgesellschaft m.b.H.

发明人： KOLLER, Kurt ,  SCHWARZ, Franz

IPC分类号： A61K31/22 ,  A61K47/12 ,  A61K47/10

CPC分类号： A61K9/0019 ,  A61K31/221 ,  A61K47/10 ,  A61K47/12

摘要： The preparation of an improved galenic delivery form of valnemulin, which is notable for its good tolerance and stability in storage, is described. The new delivery form in question is a non-aqueous or oily injection formulation, which is obtainable by means of in situ preparation and subsequent stabilisation of the free, relatively unstable base of the active ingredient. A further aspect of the present invention concerns the usage of such an injection formulation in a method of treating infectious diseases in productive livestock or domestic animals.

公开(公告)号：EP1235566B1

公开(公告)日：2005-03-23

申请号：EP00990671.0

申请日：2000-12-07

申请人： Novartis AG ,  Novartis Pharma GmbH

发明人： KOLLER, Kurt ,  SCHWARZ, Franz

IPC分类号： A61K31/22 ,  A61K47/12 ,  A61K47/10 ,  A61P31/00

CPC分类号： A61K9/0019 ,  A61K31/221 ,  A61K47/10 ,  A61K47/12

摘要： The preparation of an improved galenic delivery form of valnemulin, which is notable for its good tolerance and stability in storage, is described. The new delivery form in question is a non-aqueous or oily injection formulation, which is obtainable by means of in situ preparation and subsequent stabilisation of the free, relatively unstable base of the active ingredient. A further aspect of the present invention concerns the usage of such an injection formulation in a method of treating infectious diseases in productive livestock or domestic animals.