专利检索 ap:("Novartis AG" OR "The Trustees of The University of Pennsylvania") AND inv:"KAWALEKAR, Omkar, U." 第 1 页

1.

发明公开
METHODS FOR IMPROVING THE EFFICACY AND EXPANSION OF IMMUNE CELLS 审中-公开

公开(公告)号：EP3325504A1

公开(公告)日：2018-05-30

申请号：EP16750306.9

申请日：2016-07-21

申请人： Novartis AG , The Trustees of The University of Pennsylvania

发明人： BEDOYA, Felipe , GHASSEMI, Saba , JUNE, Carl, H. , KAWALEKAR, Omkar, U. , LEVINE, Bruce, L. , MELENHORST, Jan, J. , MILONE, Michael, C. , POWELL, Daniel, Jr., J. , ZHENG, Zoe

IPC分类号： C07K14/725 , C07K16/30 , A61K48/00

CPC分类号： C12N5/0636 , A61K35/17 , C07K14/7051 , C07K14/70517 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K16/2803 , C07K16/30 , C07K2317/622 , C07K2319/03 , C07K2319/33 , C07K2319/74 , C12N5/0087 , C12N2501/2302 , C12N2501/2307 , C12N2501/2315 , C12N2501/50 , C12N2510/00 , C12N2740/16043

摘要： The invention provides methods of making immune effector cells (e.g., T cells, NK cells) that can be engineered to express a chimeric antigen receptor (CAR), compositions and reaction mixtures comprising the same, and methods of treatment using the same.