公开(公告)号：EP2010521A1

公开(公告)日：2009-01-07

申请号：EP07760654.9

申请日：2007-04-13

申请人： Novartis Ag

发明人： SHAFER, Cynthia ,  WALTER, Annette ,  LINDVALL, Mika, K. ,  GESNER, Thomas ,  DOYLE, Laura

IPC分类号： C07D403/04 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  C07D471/04 ,  A61K31/416 ,  A61K31/4162 ,  A61K31/437 ,  A61P35/00

CPC分类号： C07D403/04 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D471/04

摘要： New compounds capable of acting as CDC7 inhibitors are provided. The compounds are useful either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of CDC7 mediated diseases, such as cancer. The compounds have the Formula (I) or (II), where the values of the variables are defined herein (I), (II).