公开(公告)号：EP2569002A1

公开(公告)日：2013-03-20

申请号：EP11718398.8

申请日：2011-05-09

申请人： Novo Nordisk A/S

发明人： ANDRESEN, Lene ,  HANSEN, Rosa Rebecca Erritzøe ,  JEPPESEN, Per

IPC分类号： A61K38/28

CPC分类号： A61K38/28

摘要： The invention concerns a process for preparing a pharmaceutical formulation comprising an insulin derivative, wherein the process comprises dissolving an insulin derivative in water, adjusting the pH of the solution to a pH above 7.2, adding a zinc solution while stirring continuously and adjusting the pH to the target pH of the formulation.

公开(公告)号：EP3821905A1

公开(公告)日：2021-05-19

申请号：EP20208962.9

申请日：2017-12-15

申请人： Novo Nordisk A/S

发明人： NORRMAN, Mathias ,  HOSTRUP, Susanne ,  STEENSGAARD, Dorte Bjerre ,  STRAUSS, Holger Martin ,  HANSEN, Rosa Rebecca Erritzøe ,  HAVELUND, Svend ,  SCHLEIN, Morten ,  PEDERSEN, Jesper Søndergaard

IPC分类号： A61K38/28 ,  A61K38/26 ,  A61K47/02 ,  A61K9/00 ,  A61P5/48

摘要： The present invention is in the field of pharmaceutical compositions for the treatment of medical conditions relating to diabetes. More specifically the invention provides pharmaceutical compositions comprising a long-acting acylated derivative of a human insulin analogue and semaglutide, and to the medical use of such compositions for basal insulin administration therapy.

公开(公告)号：EP2569002B1

公开(公告)日：2016-10-26

申请号：EP11718398.8

申请日：2011-05-09

申请人： Novo Nordisk A/S

发明人： ANDRESEN, Lene ,  HANSEN, Rosa Rebecca Erritzøe ,  JEPPESEN, Per

IPC分类号： A61K38/28

CPC分类号： A61K38/28