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1.
公开(公告)号:EP3823715A1
公开(公告)日:2021-05-26
申请号:EP19773504.6
申请日:2019-07-18
申请人: Novocure GmbH
发明人: BOMZON, Zeev , HERSHKOVICH, Hadas Sara , NAVEH, Ariel , LEVI, Shay , URMAN, Noa
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公开(公告)号:EP4226967A1
公开(公告)日:2023-08-16
申请号:EP23170927.0
申请日:2021-09-29
申请人: Novocure GmbH
发明人: FARBER, Ori , NAVEH, Ariel , WASSERMAN, Yoram
摘要: A system to apply tumor treating fields to a torso of a subject's body, the system comprising: a first transducer adapted to be located at a first location of the subject's body, the first location being on the torso of the subject's body; a second transducer adapted to be located at a second location of the subject's body, the second location being below the torso of the subject's body; a voltage generator (907) adapted to be coupled to the first transducer and the second transducer and provide a first voltage to the first transducer and a second voltage to the second transducer; and a controller (908) coupled to the voltage generator (907), the controller (908) comprising one or more processors and memory accessible by the one or more processors, the memory storing instructions that, when executed by the one or more processors, cause the controller (908) to instruct the voltage generator (907) to generate the first voltage and the second voltage to induce an electric field in the torso of the subject's body, the electric field having field intensities of at least 1.0 V/cm in at least 50% of volume of the torso of the subject's body.
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公开(公告)号:EP4132640A2
公开(公告)日:2023-02-15
申请号:EP21787051.8
申请日:2021-09-29
申请人: Novocure GmbH
发明人: FARBER, Ori , NAVEH, Ariel , WASSERMAN, Yoram
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公开(公告)号:EP4363047A1
公开(公告)日:2024-05-08
申请号:EP22743901.5
申请日:2022-06-30
申请人: Novocure GmbH
发明人: GILADI, Moshe , AVIGDOR, Lilach , NAVEH, Ariel
IPC分类号: A61N1/40
CPC分类号: A61N1/40
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公开(公告)号:EP4137195A1
公开(公告)日:2023-02-22
申请号:EP22198125.1
申请日:2019-10-11
申请人: Novocure GmbH
发明人: BOMZON, Zeev , NAVEH, Ariel , YESHARIM, Ofir
摘要: This application discloses configurations for arranging transducer arrays on a person's head to impose tumor treating fields (TTFields) in the brain at field strengths that are as uniform as possible throughout the entire brain. In some embodiments, L-shaped sets of electrodes are positioned near the right and left ears, each with a horizontal arm above the ear and a vertical arm behind the ear. Optionally, these embodiments may be combined with a second pair of electrodes positioned on top of the head and behind the neck. In other embodiments, one pair of electrodes is positioned above the right ear and on the left/rear portion of the neck, and a second pair of electrodes is positioned above the left ear and on the right/rear portion of the neck. These configurations improve the uniformity of the electric fields imposed throughout the brain, and are particularly useful for preventing and/or treating metastases.
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6.
公开(公告)号:EP3967361A1
公开(公告)日:2022-03-16
申请号:EP21205777.2
申请日:2019-07-18
申请人: Novocure GmbH
发明人: BOMZON, Zeev , HERSHKOVICH, Hadas Sara , NAVEH, Ariel , LEVI, Shay , URMAN, Noa
摘要: The planning of treatment using tumor treating fields (TTFields) in a portion of a subject's body (e.g., the subject's head) can be improved by obtaining an image of the body portion, and generating, based on the image, a 3D model of electrical conductivity. A target volume within the 3D model is identified, and a set of model electrodes is added to the 3D model at given locations. Then, for each voxel in the target volume, the power loss density (PLD) that will be present when TTFields are eventually applied is determined. The same process can be repeated for a plurality of different electrode locations, and the set of electrode locations that yields the best PLD selected.
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公开(公告)号:EP3954314A1
公开(公告)日:2022-02-16
申请号:EP21188422.6
申请日:2020-02-26
申请人: Novocure GmbH
发明人: WASSERMAN, Yoram , BOMZON, Zeev , HERSHKOVICH, Hadas Sara , NAVEH, Ariel , GILADI, Moshe , KIRSON, Eilon , BAR-TAL, Golan , VOLOSHIN-SELA, Tali
摘要: Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.
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公开(公告)号:EP4021559A1
公开(公告)日:2022-07-06
申请号:EP20775405.2
申请日:2020-08-28
申请人: Novocure GmbH
发明人: AVRAHAM, Yissachar , NAVEH, Ariel , BOMZON, Zeev
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9.
公开(公告)号:EP3967362A1
公开(公告)日:2022-03-16
申请号:EP21205805.1
申请日:2019-07-18
申请人: Novocure GmbH
发明人: BOMZON, Zeev , HERSHKOVICH, Hadas Sara , NAVEH, Ariel , LEVI, Shay , URMAN, Noa
摘要: The planning of treatment using tumor treating fields (TTFields) in a portion of a subject's body (e.g., the subject's head) can be improved by obtaining an image of the body portion, and generating, based on the image, a 3D model of electrical conductivity. A target volume within the 3D model is identified, and a set of model electrodes is added to the 3D model at given locations. Then, for each voxel in the target volume, the power loss density (PLD) that will be present when TTFields are eventually applied is determined. The same process can be repeated for a plurality of different electrode locations, and the set of electrode locations that yields the best PLD selected.
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公开(公告)号:EP3917423A1
公开(公告)日:2021-12-08
申请号:EP20710293.0
申请日:2020-02-26
申请人: Novocure GmbH
发明人: BOMZON, Zeev , HERSHKOVICH, Hadas Sara , NAVEH, Ariel , GILADI, Moshe , KIRSON, Eilon , BAR-TAL, Golan , VOLOSHIN-SELA, Tali , WASSERMAN, Yoram
IPC分类号: A61B18/14
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