公开(公告)号：EP1727560A2

公开(公告)日：2006-12-06

申请号：EP05712439.8

申请日：2005-01-27

申请人： Nuvelo, Inc. ,  KIRIN BEER KABUSHIKI KAISHA

发明人： BOYLE, Bryan, J. ,  FUNK, Walter ,  KAKITANI, Makoto ,  OSHIMA, Takeshi ,  PARK, Eun, Ju ,  TANG, Tom, Y. ,  YAGI, Mikio ,  TMIZUKA, Kazuma

IPC分类号： A61K38/18

CPC分类号： G01N33/5088 ,  A01K67/0275 ,  A01K2217/072 ,  A01K2227/105 ,  A01K2267/01 ,  A61K38/1709 ,  A61K48/005 ,  C07K14/475 ,  C12N15/8509 ,  C12N2799/022 ,  C12N2800/30

摘要： The invention relates to pharmaceutical compositions comprising gastrointestinal proliferative factor (GIPF) polynucleotides and polypeptides. The invention further relates to the therapeutic use of GIPF to prevent or treat conditions or disorders associated with the degeneration of the epithelial mucosa.