-
公开(公告)号：EP0450472B1
公开(公告)日：1997-05-14
申请号：EP91104816.3
申请日：1991-03-26
申请人： ONCOGEN LIMITED PARTNERSHIP , UNITED STATES GOVERNMENT as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人： Salahuddin, Syed Zaki , Nakamura, Shuji , Gallo, Robert C. , Radka, Susan F. , Linsley, Peter S. , Shoyab, Mohammed
IPC分类号： C12P21/08 , A61K39/395
-
2.发明公开Monoclonal antibodies that inhibit growth of kaposi's sarcoma 失效MonoklonaleAntikörper，die das Wachstum des Karposisarkomas inhibitsi。
公开(公告)号：EP0450472A1
公开(公告)日：1991-10-09
申请号：EP91104816.3
申请日：1991-03-26
申请人： ONCOGEN LIMITED PARTNERSHIP , UNITED STATES GOVERNMENT as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人： Salahuddin, Syed Zaki , Nakamura, Shuji , Gallo, Robert C. , Radka, Susan F. , Linsley, Peter S. , Shoyab, Mohammed
IPC分类号： C12P21/08 , A61K39/395
摘要： The present invention involves the use of monoclonal antibodies specific for Oncostatin M to inhibit the growth potentiating effect of Oncostatin M on Kaposi's Sarcoma associated with AIDS. In particular neutralizing anti-Oncostatin M antibodies inhibit the growth of Kaposi's Sarcoma which is potentiated and maintained by Oncostatin M or a factor found in conditioned media of an HTLV-II transformed T cell line.
摘要翻译： 本发明涉及使用针对制瘤素M特异性的单克隆抗体来抑制制瘤素M对与AIDS相关的卡波西肉瘤的生长增强作用。 特别是中和抗制药素M抗体抑制卡波西肉瘤的生长，其通过制瘤素M或在HTLV-II转化的T细胞系的条件培养基中发现的因子来增强和维持。
-
搜索结果
2 条记录 (耗时 0.016 秒)
