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公开(公告)号:EP0745685B1
公开(公告)日:2002-01-16
申请号:EP96108641.0
申请日:1996-05-30
发明人: Takeshita, Hitoshi , Morita, Hiroshi , Fujiwara, Akira , Kaneda, Yasutaka , Watanabe, Tohru , Hayashi, Taizou , Uchida, Kohji , Matsuo, Yushi , Horio, Takekazu
IPC分类号: C12Q1/533
CPC分类号: G01N33/6896 , C12Q1/533 , G01N2800/2871
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公开(公告)号:EP0745685A1
公开(公告)日:1996-12-04
申请号:EP96108641.0
申请日:1996-05-30
发明人: Takeshita, Hitoshi , Morita, Hiroshi , Fujiwara, Akira , Kaneda, Yasutaka , Watanabe, Tohru , Hayashi, Taizou , Uchida, Kohji , Matsuo, Yushi , Horio, Takekazu
IPC分类号: C12Q1/533
CPC分类号: G01N33/6896 , C12Q1/533 , G01N2800/2871
摘要: A sample is treated with a phosphoglyceric acid mutase (PGAM) inhibitor (polythionic acid (salt) such as potassium tetrathionate) to inactivate the M-type isozyme activity and the B-type PGAM is quantified by determining PGAM isozymes by a rate assay. The B-type PGAM is a novel marker for cerebral apoplexy, and the diagnosis of cerebral apoplexy is enabled by assaying it.
摘要翻译: 用磷酸甘油酸变位酶(PGAM)抑制剂(多硫酸(盐)如四硫代硫酸钾)处理样品以灭活M型同功酶活性,并通过速率测定法测定PGAM同功酶来定量B型PGAM。 B型PGAM是脑中风的新型标志物,通过分析它可以确定脑中风的诊断。
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