公开(公告)号：EP4491612A1

公开(公告)日：2025-01-15

申请号：EP23766793.6

申请日：2023-03-06

Applicant: OSAKA UNIVERSITY

Inventor： FUKASE Koichi ,  TOYOSHIMA Atsushi ,  SHINOHARA Atsushi ,  SHIRAKAMI Yoshifumi ,  KANEDA Kazuko ,  SHIMOYAMA Atsushi ,  KADONAGA Yuichiro

IPC: C07C231/12 ,  C07B59/00 ,  C25B3/11 ,  C25B3/27 ,  C25B15/023 ,  C25B15/029 ,  C25B15/08 ,  A61K51/00

Abstract: Provided is a novel method for labeling a radionuclide such as 211 At with a high radiochemical yield under more convenient and stable conditions.
A production method of an aryl compound labeled with a radionuclide includes a step of applying a voltage to a solution A containing a radionuclide and electrolytically oxidizing the radionuclide; and a step of mixing the solution A and a solution B containing a compound S having a halogenated aryl group to substitute a halogen atom on the aryl group of the compound S with the radionuclide.

公开(公告)号：EP4151198A1

公开(公告)日：2023-03-22

申请号：EP21804042.6

申请日：2021-05-14

Applicant: OSAKA UNIVERSITY

Inventor： KATO Hiroki ,  FUKASE Koichi ,  KABAYAMA Kazuya ,  SHIMOYAMA Atsushi ,  KADONAGA Yuichiro ,  TOYOSHIMA Atsushi ,  SHINOHARA Atsushi ,  KANEDA Yasufumi ,  NISHIKAWA Tomoyuki

IPC: A61K20060101

Abstract: The present invention relates to a gold nanoparticle-containing medicine, and a treatment of a proliferative disease using the medicine. The present invention also relates to a gold nanoparticle-containing medicine that is bound to an alpha radioactive nucleus, and a treatment of a proliferative disease using the medicine.