公开(公告)号：EP1675860B1

公开(公告)日：2011-09-21

申请号：EP04795392.2

申请日：2004-10-14

申请人： OSI Pharmaceuticals, Inc.

发明人： BECK, Patricia, Anne ,  CESARIO, Cara ,  COX, Matthew ,  DONG, Han-Qing ,  FOREMAN, Kenneth ,  MULVIHILL, Mark, Joseph ,  NIGRO, Anthony, Innocenzo ,  SAROGLOU, Lydia ,  STEINIG, Arno, G. ,  SUN, Yingchuan ,  WENG, Qinghua ,  WERNER, Douglas ,  WILKES, Robin ,  WILLIAMS, Jonathan

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein Q1 and R1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.

公开(公告)号：EP1675860A2

公开(公告)日：2006-07-05

申请号：EP04795392.2

申请日：2004-10-14

申请人： OSI Pharmaceuticals, Inc.

发明人： BECK, Patricia, Anne ,  CESARIO, Cara ,  COX, Matthew ,  DONG, Han-Qing ,  FOREMAN, Kenneth ,  MULVIHILL, Mark, Joseph ,  NIGRO, Anthony, Innocenzo ,  SAROGLOU, Lydia ,  STEINIG, Arno, G. ,  SUN, Yingchuan ,  WENG, Qinghua ,  WERNER, Douglas ,  WILKES, Robin ,  WILLIAMS, Jonathan

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： Compounds of the formula (I) and pharmaceutically acceptable salts thereof, wherein Q1 and R1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of various diseases and conditions that respond to treatment by inhibition of tyrosine kinases.