专利检索 ap:("OSI Pharmaceuticals, LLC") AND inv:"WERNER, Douglas, S." 第 1 页

1.

发明公开
PROCESS FOR SUBSTITUTED 3-AMINO-5-OXO-4,5-DIHYDRO-[1,2,4]TRIAZINES 审中-公开
标题翻译： PROCESS FOR取代的3-氨基-5-氧代-4,5-二氢[1,2,4]三嗪

公开(公告)号：EP2451792A2

公开(公告)日：2012-05-16

申请号：EP10797821.5

申请日：2010-07-08

申请人： OSI Pharmaceuticals, LLC

发明人： DONG, Hanqing , MAO, Yunyu , MULVIHILL, Kristen, Michelle , RECHKA, Josef, A. , WERNER, Douglas, S.

IPC分类号： C07D253/06 , C07D487/04 , C07D403/04

CPC分类号： C07D253/075 , C07D487/04

摘要： Processes including preparation of
trans -4-[(3-amino-5-oxo-4,5-dihydro-[1,2,4]triazin-6-ylmethyl)-carbamoyl]-cyclohexanecarboxylic acid methyl ester, and its conversion to
trans -4-(4-amino-5-susbtituted-imidazo[5,1-ƒ][1,2,4]triazin-7-yl)-cyclohexanecarboxylic acid compounds.