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1.发明授权LOW HYGROSCOPIC ARIPIPRAZOLE DRUG SUBSTANCE AND PROCESSES FOR THE PREPARATION THEREOF 有权阿立哌唑ACTIVE较低的吸湿性及其制备方法
公开(公告)号：EP1330249B1
公开(公告)日：2006-04-05
申请号：EP02782507.4
申请日：2002-09-25
发明人： BANDO, Takuji , AOKI, Satoshi , KAWASAKI, Junichi , ISHIGAMI, Makoto , TANIGUCHI, Youichi , YABUUCHI, Tsuyoshi , FUJIMOTO, Kiyoshi , NISHIOKA, Y. 5-3 Nakagirai Aza , KOBAYASHI, Noriyuki , FUJIMURA, Tsutomu , TAKAHASHI, Masanori , ABE, Kaoru , NAKAGAWA, Tomonori Grace 78-205, 78 Sasagino Aza , SHINHAMA, Koichi , UTSUMI, Naoto , TOMINAGA, Michiaki , OI, Yoshihiro , YAMADA, Shohei , TOMIKAWA, Kenji
IPC分类号： A61K31/496 , C07D215/22 , A61P25/18
CPC分类号： C07D215/227 , C07B2200/13 , C07D215/22 , Y10T428/2982
摘要： The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period.
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2.发明公开LOW HYGROSCOPIC ARIPIPRAZOLE DRUG SUBSTANCE AND PROCESSES FOR THE PREPARATION THEREOF 有权阿立哌唑ACTIVE较低的吸湿性及其制备方法
公开(公告)号：EP1330249A1
公开(公告)日：2003-07-30
申请号：EP02782507.4
申请日：2002-09-25
发明人： BANDO, Takuji , AOKI, Satoshi , KAWASAKI, Junichi , ISHIGAMI, Makoto , TANIGUCHI, Youichi , YABUUCHI, Tsuyoshi , FUJIMOTO, Kiyoshi , NISHIOKA, Y.5-3 Nakagirai Aza , KOBAYASHI, Noriyuki , FUJIMURA, Tsutomu , TAKAHASHI, Masanori , ABE, Kaoru , NAKAGAWA, TomonoriGrace 78-205,78 Sasagino Aza , SHINHAMA, Koichi , UTSUMI, Naoto , TOMINAGA, Michiaki , OI, Yoshihiro , YAMADA, Shohei , TOMIKAWA, Kenji
IPC分类号： A61K31/496 , C07D215/22 , A61P25/18
CPC分类号： C07D215/227 , C07B2200/13 , C07D215/22 , Y10T428/2982
摘要： The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the aripiprazole anhydride crystals is stored for an extended period.
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