OPHTHALMIC IMAGING DEVICE
    1.
    发明公开

    公开(公告)号:EP3799777A1

    公开(公告)日:2021-04-07

    申请号:EP19201433.0

    申请日:2019-10-04

    申请人: Optos PLC

    IPC分类号: A61B3/12 A61B3/15 A61B3/10

    摘要: An ophthalmic device (10) for imaging an eye (70), wherein a scanning element (40) scans a first portion of light beam across a region of an eye via a light guiding component (50), and a second portion of the light beam is reflected back by the light guiding component. The ophthalmic device further comprises: a light detector (20) to detect light reflected from eye and guided to the light detector by the light guiding component; and a dynamic amplitude mask which receives the light reflected from the eye and the light reflected back by the light guiding component, and has an unmasked portion to allow light reflected from the eye to reach the light detector, and a masked portion whose spatial distribution varies with a scan angle such that the masked portion prevents light reflected back by the light guiding component from reaching the light detector during the scan.

    OPTICAL COHERENCE TOMOGRAPHY INSTRUMENT AND OPTICAL COHERENCE TOMOGRAPHY METHOD

    公开(公告)号:EP4029431A1

    公开(公告)日:2022-07-20

    申请号:EP21207444.7

    申请日:2021-11-10

    申请人: Optos PLC

    IPC分类号: A61B3/10 A61B3/12

    摘要: An optical coherence tomography instrument suitable for imaging a retina is disclosed. In the instrument, an adjustable optical frequency shifter, which can be or include an acousto-optic modulator or electro-optic modulator, is arranged either (i) between a coupler and a reference optical system, (ii) in a reference optical system, (iii) between the coupler and a front-end optical system, or (iv) in a front-end optical system. The optical frequency of reference light or signal light may adjustably be increased or decreased. In operation, a subject is arranged such that its retina is in the focal depth of the front-end optical system. The increase or decrease in the optical frequency of the reference light or the sample light can be adjusted. Thereby, an interferogram representing a depth structure at the retina obtained between returning signal light and returning reference light may be brought to lie within a detection bandwidth of the instrument.

    OPTICAL COHERENCE TOMOGRAPHY INSTRUMENT AND OPTICAL COHERENCE TOMOGRAPHY METHOD

    公开(公告)号:EP4029430A1

    公开(公告)日:2022-07-20

    申请号:EP21151419.5

    申请日:2021-01-13

    申请人: Optos PLC

    IPC分类号: A61B3/10 A61B3/12

    摘要: An optical coherence tomography instrument suitable for imaging a retina is disclosed. In the instrument, an adjustable optical frequency shifter, which can be an acousto-optic modulator, is arranged either (i) between a coupler and a reference optical system, (ii) in a reference optical system, (iii) between the coupler and a front-end optical system, or (iv) in a front-end optical system. The optical frequency of reference light or signal light may adjustably be increased or decreased. In operation, a subject is arranged such that its retina is in the focal depth of the front-end optical system. The increase or decrease in the optical frequency of the reference light or the sample light can be adjusted. Thereby, an interferogram representing a depth structure at the retina obtained between returning signal light and returning reference light may be brought to lie within a detection bandwidth of the instrument.

    NON-CONFOCAL POINT-SCAN FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP4276405A1

    公开(公告)日:2023-11-15

    申请号:EP23169185.8

    申请日:2023-04-21

    申请人: Optos PLC

    IPC分类号: G01B9/02 G01B9/02091

    摘要: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.

    SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP3900609A1

    公开(公告)日:2021-10-27

    申请号:EP21168558.1

    申请日:2021-04-15

    申请人: Optos PLC

    IPC分类号: A61B3/10 G01B9/02

    摘要: A swept-source OCT imaging system for imaging a region (90) of an object (70), comprising: a swept light source (10) which generates a beam (80) of varying wavelength; a scanning element (40) which scans the beam across the object; an interferometer (410) which generates interference light by combining light scattered by the object (owing to the scan) with reference light; a photodetector (50) which generates an electrical signal (S) having frequency components spanning a frequency band and caused by interference of the scattered light with the reference light; a band-pass filter module (420) which band-pass filters the electrical signal; and a sample acquisition module (440) which samples the filtered electrical signal. The band-pass filter module extracts at least some of the frequency components spanning the frequency band from the electrical signal. The sample acquisition module band-pass samples the filtered electrical signal.

    IMAGING TARGET MOVEMENT COMPENSATION IN A FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP4386312A1

    公开(公告)日:2024-06-19

    申请号:EP22214175.6

    申请日:2022-12-16

    申请人: Optos PLC

    摘要: A Fourier-domain optical coherence tomography imaging system (10) comprising an Fourier-domain optical coherence tomography scanner (20) arranged to generate complex optical coherence tomography data (25) by performing a scan of an imaging target (30) to acquire samples whose complex values are indicative of an optical property of the imaging target at respective scan locations in the imaging target. The imaging system (10) further comprises a controller (40) arranged to calculate a two-dimensional cross-correlation using phase information of the acquired samples, and control the scanner (20), based on the calculated cross-correlation, to compensate for relative movement between the imaging target (30) and the scanner (20) during the scan.

    NON-CONFOCAL POINT-SCAN FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP4276405A8

    公开(公告)日:2024-01-10

    申请号:EP23169185.8

    申请日:2023-04-21

    申请人: Optos PLC

    IPC分类号: G01B9/02 G01B9/02091

    摘要: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.

    NON-CONFOCAL POINT-SCAN FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP4276404A8

    公开(公告)日:2023-12-27

    申请号:EP22173231.6

    申请日:2022-05-13

    申请人: Optos PLC

    IPC分类号: G01B9/02 G01B9/02091

    摘要: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.

    NON-CONFOCAL POINT-SCAN FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM

    公开(公告)号:EP4276404A1

    公开(公告)日:2023-11-15

    申请号:EP22173231.6

    申请日:2022-05-13

    申请人: Optos PLC

    IPC分类号: G01B9/02 G01B9/02091

    摘要: A non-confocal point-scan Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a scanning system arranged to perform a two-dimensional point scan of a light beam across an imaging target, and collect light scattered by the imaging target; a light detector arranged to generate a detection signal based on an interference between a reference light and the light collected by the scanning system. The OCT imaging system further comprises hardware arranged to: generate complex volumetric OCT data of the imaging target based on the detection signal, the OCT data including a component which, when the OCT data is processed to generate an enface projection of the OCT data, provides a defocusing and/or distortion in the enface projection; and generate corrected OCT data by executing a correction algorithm which uses phase information in the OCT data to remove at least some of the component from the OCT data.

    OPHTHALMIC CONFOCAL OCT IMAGING SYSTEM
    10.
    发明公开

    公开(公告)号:EP3977915A1

    公开(公告)日:2022-04-06

    申请号:EP20199575.0

    申请日:2020-10-01

    申请人: Optos PLC

    IPC分类号: A61B3/10 G01B9/02 G02B21/00

    摘要: A confocal OCT imaging system (10) for imaging a region (20) of a subject's eye (30), comprising: a light source (40); an illumination module (50) comprising a mask (310) having transmissive portions (315) through which light from the light source propagates to form respective non-overlapping light beams (90), the illumination module scanning the non-overlapping beams across the region such that each point in the region is illuminated by a respective one of the non-overlapping beams during the scan; an interferometer (60) which generates reference light based on the light from the light source, and generate interference light by combining, for each beam, light from the beam which has been reflected from the region with the reference light; a photodetector element array (70) which detect the interference light; and a tomographic image data generating module (80) which generates a tomographic image of the region based on the detected interference light.